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Article
Open AccessMiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells
Natural killer (NK) cells are important in host to eliminate circulating tumour cells (CTCs) in turn preventing the development of tumour cells into metastasis but the mechanisms are very poorly defined. Here ...
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Article
Open AccessMulti-therapeutic effects of human adipose-derived mesenchymal stem cells on radiation-induced intestinal injury
Radiation-induced intestinal injuries (RIII) commonly occur in patients who suffer from pelvic or abdominal cancer. However, current management of these injuries is ineffective. Recently, mesenchymal stem cell...
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Chapter
Factors Affecting Formation and Structure of DNA Intrastrand Cross-Links by Dinuclear Platinum Complexes
Dinuclear platinum complexes are currently undergoing pre-clinical evaluation. The development of this series has been driven by the hypothesis that a different spectrum of antitumor activity in comparison to ...
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Chapter and Conference Paper
Bis(Platinum) Complexes. Chemistry, Antitumor Activity and DNA-Binding
Bis(platinum) complexes of general formula [PtXnL3-n 2(diamine)](2-n)+ (X = for example CI, L = for example NH3, n = 1,2, and where diamine is most generally represented as H2N-R-NH2, with R a linea...