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Chapter and Conference Paper
Bis(Platinum) Complexes. Chemistry, Antitumor Activity and DNA-Binding
Bis(platinum) complexes of general formula [PtXnL3-n 2(diamine)](2-n)+ (X = for example CI, L = for example NH3, n = 1,2, and where diamine is most generally represented as H2N-R-NH2, with R a linea...
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Chapter
Biodistribution and Pharmacokinetics of 195mPt-Labeled cis-Dichloro-trans-Dihydroxo-bis(Isopropylamine) Platinum (IV), CHIP, In the Normal Female Fischer 344 Rat
The discovery and successful clinical application of the potent antitumor compound, cis-Dichlorodiammineplatinum(II), cis-DDP* has stimulated considerable interest in develo** effective but less toxic secondgen...