3 Result(s)
within
Y. Humblet
Epidemiology
-
Article
Tallimustine in advanced previously untreated colorectal cancer, a phase II study
Tallimustine is a novel benzoyl mustard derivative from distamycin A with a unique mode of action. It is a DNA minor groove binder and produces highly sequence-specific alkylations. Previous studies have shown...
-
Article
Open AccessAssociation of progression-free survival with patient-reported outcomes and survival: results from a randomised phase 3 trial of panitumumab
In a randomised phase 3 trial, panitumumab significantly improved progression-free survival (PFS) in patients with refractory metastatic colorectal cancer (mCRC). This analysis characterises the association of...
-
Article
Open AccessPathological responses after angiogenesis or EGFR inhibitors in metastatic colorectal cancer depend on the chemotherapy backbone
Optimal preoperative treatment before colorectal cancer metastases (CRCM) resection remains unclear. This study evaluated pathological responses (pR) in CRCM resected after chemotherapy alone or combined with ...
