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  1. Article

    Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-κB pathway

    Y Kfoury, R Nasr, O Hermine, H de Thé, A Bazarbachi in Cell Death & Differentiation (2005)

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    Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome

    Constitutive activation of the NF-κB pathway by the Tax oncoprotein plays a crucial role in the proliferation and transformation of HTLV-I infected T lymphocytes. We have previously shown that Tax ubiquitylati...

    Y Kfoury, R Nasr, A Favre-Bonvin, M El-Sabban, N Renault, M-L Giron… in Oncogene (2008)