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    Article

    KSHV-transformed primary effusion lymphoma cells induce a VEGF-dependent angiogenesis and establish functional gap junctions with endothelial cells

    Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of primary effusion lymphoma (PEL) and of Kaposi's sarcoma. PEL is an aggressive proliferation of B cells with poor prognosis. We evaluated...

    L Haddad, H El Hajj, R Abou-Merhi, Y Kfoury, R Mahieux, M El-Sabban in Leukemia (2008)

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    Article

    Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome

    Constitutive activation of the NF-κB pathway by the Tax oncoprotein plays a crucial role in the proliferation and transformation of HTLV-I infected T lymphocytes. We have previously shown that Tax ubiquitylati...

    Y Kfoury, R Nasr, A Favre-Bonvin, M El-Sabban, N Renault, M-L Giron in Oncogene (2008)