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  1. Article

    Open Access

    Single-cell transcriptomic profiling reveals immune cell heterogeneity in acute myeloid leukaemia peripheral blood mononuclear cells after chemotherapy

    Acute myeloid leukaemia (AML) is a heterogeneous disease characterised by the rapid clonal expansion of abnormally differentiated myeloid progenitor cells residing in a complex microenvironment. However, the i...

    Xuqiao Hu, Dongyan Cao, Zhenru Zhou, Zhaoyang Wang, Jieying Zeng… in Cellular Oncology (2024)

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  2. No Access

    Article

    Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria

    The emergence and rapid spread of the mobile colistin resistance gene mcr-1 among bacterial species and hosts significantly challenge the efficacy of “last-line” antibiotic colistin. Previously, we reported silve...

    Qi Zhang, Minji Wang, Xuqiao Hu, Aixin Yan… in JBIC Journal of Biological Inorganic Chemi… (2023)

  3. No Access

    Article

    One step further into the blackbox: a pilot study of how to build more confidence around an AI-based decision system of breast nodule assessment in 2D ultrasound

    To investigate how a DL model makes decisions in lesion classification with a newly defined region of evidence (ROE) by incorporating “explainable AI” (xAI) techniques.

    Fa** Dong, Ruilian She, Chen Cui, Siyuan Shi, Xuqiao Hu… in European Radiology (2021)