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Article
CHI3L1 promotes myocardial fibrosis via regulating lncRNA TUG1/miR-495-3p/ETS1 axis
Abnormal levels of CHI3L1 and lnc TUG1 are often associated with myocardial fibrosis, and their specific expressions may be closely related to the process of myocardial fibrosis. In addition, CHI3L1 was found ...
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Article
Performance evolution of self-compacting concrete for ballastless track based on high-cycle fatigue damage constitutive model
The self-compacting concrete (SCC) filling layer of CRTS III ballastless track is prone to high-cycle fatigue damage under repeated train loads and complex environments. Based on the technology that fully coup...
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Article
Open AccessRehabilitation robot following motion control algorithm based on human behavior intention
In response to the current problem of low intelligence of mobile lower limb motor rehabilitation aids. This paper proposes an intelligent control scheme based on human movement behavior in order to control the...
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Article
Open AccessCorrection: Safety and efficacy of using portable coagulation monitor for INR examination after left‑sided mechanical prosthetic valve replacement
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Open AccessSafety and efficacy of using portable coagulation monitor for INR examination after left-sided mechanical prosthetic valve replacement
Time in therapeutic range (TTR) is an index to assess the effectiveness of anticoagulation and is important to predict the risk of bleeding and thrombosis in patients taking warfarin. In recent years, the port...
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Article
B/Ti Atomic Ratio and Al Content on Microstructure and Properties of New Neutron Absorbing Austenitic Stainless-Steel Composites
A new type of austenitic stainless-steel composite with different B/Ti atomic ratios and Al contents have been fabricated by in situ synthesis techniques. The effects of the B/Ti atomic ratio and Al content on...
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Article
Open AccessmiR-188-3p-targeted regulation of ATG7 affects cell autophagy in patients with nonobstructive azoospermia
Nonobstructive azoospermia (NOA) is one of the most difficult forms of male infertility to treat, and its pathogenesis is still unclear. miRNAs can regulate autophagy by affecting their target gene expression....
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Article
Seismic high-resolution processing method based on spectral simulation and total variation regularization constraints
There is little low-and-high frequency information on seismic data in seismic exploration, resulting in narrower bandwidth and lower seismic resolution. It considerably restricts the prediction accuracy of thi...
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Article
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
LianhuaQingwen capsule, prepared from an herbal combination, is officially recommended as treatment for COVID-19 in China. Of the serial pharmacokinetic investigations we designed to facilitate identifying Lia...
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Article
Open AccessOpen Seldinger-guided peripheral femoro-femoral cannulation technique for totally endoscopic cardiac surgery
The cannulation technique used in totally endoscopic cardiac surgery has a significant impact on the overall prognosis of patients. However, there are no large cohort studies to discuss it. Here we report on o...
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Open AccessMalaria: elimination tale from Yunnan Province of China and new challenges for reintroduction
Eradication of infectious disease is the sanctified public health and sustainable development goal around the world.
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Open AccessPRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome
The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27 di-methylation (H3K27me2) and H3K27 tri-methylation (H3K27...
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Article
A standardized pathological proposal for evaluating microvascular invasion of hepatocellular carcinoma: a multicenter study by LCPGC
Microvascular invasion (MVI) is a key pathological factor that severely affects the postoperative prognosis of patients with hepatocellular carcinoma (HCC). However, no MVI classification schemes based on stan...
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Open AccessComposition of gut and oropharynx bacterial communities in Rattus norvegicus and Suncus murinus in China
Rattus norvegicus and Suncus murinus are important reservoirs of zoonotic bacterial diseases. An understanding of the composition of gut and oropharynx bacteria in these animals is important for monitoring and pr...
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Article
Stimuli-responsive combination therapy of cisplatin and Nrf2 siRNA for improving antitumor treatment of osteosarcoma
Cisplatin is a widely applied therapeutics for the treatment of osteosarcoma. However, its clinical applications have been hindered due to low efficacy and bioavailability, and particularly frequent emergence ...
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Article
Open AccessComparisons of microbiological characteristics and antibiotic resistance of Klebsiella pneumoniae isolates from urban rodents, shrews, and healthy people
The comparisons of molecular characterization and antibiotic resistance of Klebsiella pneumoniae (KP) isolates from humans and other animal hosts are not well studied. Our goal was to compare the molecular epidem...
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Article
CelB is a suitable marker for rapid and specific identification of Klebsiella pneumoniae by the loop-mediated isothermal amplification (LAMP) assay
Klebsiella pneumoniae belongs to Enterobacteriaceae, which is the commonest bacterium causing nosocomial respiratory tract infection. It ranks second in bacteremia and urinary tract infection in gram-negative bac...
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Article
Open AccessMethicillin-resistant Staphylococcus aureus among urban rodents, house shrews, and patients in Guangzhou, Southern China
The transmission of methicillin-resistant Staphylococcus aureus (MRSA) between humans and animals has been identified in a number of countries. In this study, MRSA in urban rodents and shrews in a community was i...
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Article
Open AccessTranscatheter and intraoperative device closure and surgical repair for atrial septal defect
Transcatheter and intraoperative device closure for atrial septal defect (ASD) are widely applied to reduce the incision size and the potential for injury during cardiopulmonary bypass (CPB) in conventional su...
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Article
The Susceptibility of Primary Dermis Fibroblasts from the Chinese Tree Shrew to Human Cytomegalovirus Infection
As a universal pathogen leading to neonatal defects and transplant failure, human cytomegalovirus (HCMV) has strict species specificity and this has prevented the development of a suitable animal model for the...
