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CHI3L1 promotes myocardial fibrosis via regulating lncRNA TUG1/miR-495-3p/ETS1 axis
Abnormal levels of CHI3L1 and lnc TUG1 are often associated with myocardial fibrosis, and their specific expressions may be closely related to the process of myocardial fibrosis. In addition, CHI3L1 was found ...
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Stimuli-responsive combination therapy of cisplatin and Nrf2 siRNA for improving antitumor treatment of osteosarcoma
Cisplatin is a widely applied therapeutics for the treatment of osteosarcoma. However, its clinical applications have been hindered due to low efficacy and bioavailability, and particularly frequent emergence ...
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Article
Open AccessPredicting nosocomial lower respiratory tract infections by a risk index based system
Although belonging to one of the most common type of nosocomial infection, there was currently no simple prediction model for lower respiratory tract infections (LRTIs). This study aims to develop a risk index...
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Article
Open AccessScreening and selection of peptides specific for esophageal cancer cells from a phage display peptide library
Esophageal cancer is a common malignant tumor of the gastrointestinal tract and is typically diagnosed at an advanced stage due to the absence of early clinical symptoms. Although surgery, chemotherapy, and ra...
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Chapter
The Changing Role of the Academic: Historical and Comparative Perspectives
In the postindustrial era, universities have accepted more and more responsibility for the development of a “knowledge economy.” At the same time, with the process of globalization, the external environment of...