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Article
Open AccessMRI radiomics enhances radiologists’ ability for characterizing intestinal fibrosis in patients with Crohn’s disease
We aimed to develop MRI-based radiomic models (RMs) to improve the diagnostic accuracy of radiologists in characterizing intestinal fibrosis in patients with Crohn’s disease (CD).
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Article
Cross-sectional imaging: current status and future potential in adult celiac disease
Celiac disease (CD), triggered by exposure to gluten in genetically susceptible individuals, is an immune-mediated small bowel disease affecting about 1% of the population worldwide. But the prevalence of CD v...
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Article
Clinical outcome is distinct between radiological stricture and endoscopic stricture in ileal Crohn’s disease
Differences in clinical adverse outcomes (CAO) based on different intestinal stricturing definitions in Crohn’s disease (CD) are poorly documented. This study aims to compare CAO between radiological stricture...
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Article
Hepatic mosaic enhancement pattern correlates with increased inflammatory activity and adverse therapeutic outcomes in patients with Crohn’s disease
This study aimed to evaluate the role of hepatic mosaic enhancement pattern (HMEP) on computed tomography images in the disease activity and therapeutic outcome of Crohn’s Disease (CD).
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Article
A novel identification system combining diffusion kurtosis imaging with conventional magnetic resonance imaging to assess intestinal strictures in patients with Crohn’s disease
To determine the utility of diffusion kurtosis imaging (DKI) for assessing bowel fibrosis and to establish a new magnetic resonance imaging (MRI)-based classification based on DKI and conventional MRI paramete...
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Article
Magnetisation transfer imaging adds information to conventional MRIs to differentiate inflammatory from fibrotic components of small intestinal strictures in Crohn’s disease
Identifying inflammation- or fibrosis-predominant strictures in Crohn’s disease (CD) is crucial for treatment strategies. We evaluated the additive value of magnetisation transfer (MT) to conventional MRI for ...
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Article
Open AccessA novel collagen area fraction index to quantitatively assess bowel fibrosis in patients with Crohn’s disease
A validated histopathological tool to precisely evaluate bowel fibrosis in patients with Crohn’s disease is lacking. We attempted to establish a new index to quantify the severity of bowel fibrosis in patients...
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Article
IVIM with fractional perfusion as a novel biomarker for detecting and grading intestinal fibrosis in Crohn’s disease
Intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) provides information on both perfusion and diffusion and has been used to evaluate Crohn’s disease (CD) activity and fibr...
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Article
Ability of DWI to characterize bowel fibrosis depends on the degree of bowel inflammation
Although diffusion-weighted imaging (DWI) is reported to be accurate in detecting bowel inflammation in Crohn’s disease (CD), its ability to assess bowel fibrosis remains unclear. This study assessed the role ...