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Article
Spectral Efficient Neural Network-Based M-ary Chirp Spread Spectrum Receivers for Underwater Acoustic Communication
This article addresses the challenges encountered in underwater acoustic communication (UWAC) and presents a novel approach for chirp spread spectrum (CSS) communication. CSS is recognized for its ability to a...
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Article
[Cuproptosis-related immune gene signature predicts clinical benefits from anti-PD-1/PD-L1 therapy in non-small-cell lung cancer
Non-small-cell lung cancer (NSCLC) remains the major cause of cancer-related death. Immune checkpoint inhibition has become the cornerstone treatment for NSCLC. Cuproptosis is a newly identified form of cell d...
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Article
Optimizing the tumor shrinkage threshold for evaluating immunotherapy efficacy for advanced non-small-cell lung cancer
The rise of immune checkpoint inhibitors (ICIs) in recent years has coincided with unusual clinical response patterns. Modification of the sum of longest diameters (SLD)-based threshold that reflecting dynamic...
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Chapter and Conference Paper
Self- and Semi-supervised Learning for Gastroscopic Lesion Detection
Gastroscopic Lesion Detection (GLD) plays a key role in computer-assisted diagnostic procedures. However, this task is not well studied in the literature due to the lack of labeled data and the applicable meth...
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Article
Open AccessAccuracy of next-generation sequencing for molecular profiling of small specimen of lung cancer: a prospective pilot study of side-by-side comparison
Successful practice of precision medicine in advanced lung cancers relies on therapeutic regimens tailored to individual molecular characteristics. The aim of this study was to investigate the accuracy of smal...
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Article
Correction to: Hepatotoxicity associated with PD-1 blockade antibodies in cancer patients co-infected with hepatitis B virus
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Article
Hepatotoxicity associated with PD-1 blockade antibodies in cancer patients co-infected with hepatitis B virus
The use of anti-programmed cell death-1 (PD-1) antibodies in treating malignancies is increasing; however, most registered clinical trials on anti-PD-1 antibodies exclude patients infected with hepatitis B virus ...
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Article
Efficacy and safety of PD-L1 inhibitors versus PD-1 inhibitors in first-line treatment with chemotherapy for extensive-stage small-cell lung cancer
Programmed cell death-ligand 1 inhibitors plus chemotherapy (PD-L1 + Chemo) have achieved substantial progress in extensive-stage small-cell lung cancer (ES-SCLC). However, evidence about programmed cell death...
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Chapter and Conference Paper
A Hybrid Propagation Network for Interactive Volumetric Image Segmentation
Interactive segmentation is of great importance in clinical practice for correcting and refining the automated segmentation by involving additional user hints, e.g., scribbles and clicks. Currently, interactiv...
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Article
Open AccessCombination of anti-PD-1 antibody with P-GEMOX as a potentially effective immunochemotherapy for advanced natural killer/T cell lymphoma
Advanced natural killer/T cell lymphoma (NKTL) has demonstrated poor prognosis with currently available therapies. Here, we report the efficacy of anti-programmed death 1 (PD-1) antibody with the P-GEMOX (pega...
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Chapter and Conference Paper
Peeking into Occluded Joints: A Novel Framework for Crowd Pose Estimation
Although occlusion widely exists in nature and remains a fundamental challenge for pose estimation, existing heatmap-based approaches suffer serious degradation on occlusions. Their intrinsic problem is that t...
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Article
Open AccessHepatitis B virus reactivation in cancer patients with positive Hepatitis B surface antigen undergoing PD-1 inhibition
Hepatitis B virus (HBV) reactivation is a serious complication in patients with cancers and HBV infection undergoing immunosuppressant treatment or chemotherapy. However, the safety of anti-programmed cell dea...
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Article
Open AccessFirst-line treatment for patients with advanced non-small cell lung carcinoma and high PD-L1 expression: pembrolizumab or pembrolizumab plus chemotherapy
Pembrolizumab monotherapy has become the preferred treatment for patients with advanced non-small cell lung carcinoma (NSCLC) and a programmed cell death-ligand 1 (PD-L1) tumor proportion score (TPS) of at lea...
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Article
Open AccessImmune-checkpoint inhibitor plus chemotherapy versus conventional chemotherapy for first-line treatment in advanced non-small cell lung carcinoma: a systematic review and meta-analysis
Immune-checkpoint inhibitors plus chemotherapy are emerging as effective first-line treatment in advanced non-small-cell lung carcinoma (NSCLC), but little is known about the magnitude of benefits and potentia...
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Article
Open AccessClinical characterization and outcome of primary bone lymphoma: a retrospective study of 61 Chinese patients
Primary bone lymphoma(PBL) is a rare disease. To assess the clinical characteristics, outcome, and prognostic factors of this entity in Chinese population, we retrospectively analyzed 61 PBL patients initially...
