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Article
Open AccessTargeting BRD4 mitigates hepatocellular lipotoxicity by suppressing the NLRP3 inflammasome activation and GSDMD-mediated hepatocyte pyroptosis
Nod-like receptor family pyrin-containing protein 3 (NLRP3) inflammasome plays a pathologic role in metabolic dysfunction-associated steatohepatitis (MASH), but the molecular mechanism regulating the NLRP3 inf...
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Article
Open AccessIdentification of prognostic stemness-related genes in kidney renal papillary cell carcinoma
Kidney renal papillary cell carcinoma (KIRP) is the second most prevalent malignant cancer originating from the renal epithelium. Nowadays, cancer stem cells and stemness-related genes (SRGs) are revealed to p...
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Article
An Optimal Double-Vector Finite Set Model Predictive Control Strategy Based on Deadbeat for Vienna Rectifier
The traditional finite set model predictive control for Vienna rectifier takes the minimum cost function as the control goal and outputs a single optimal vector by traversing the set of candidate vectors. Howe...
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Article
Impacts of landscape pattern evolution on typical ecosystem services in Ganjiang River Basin, China
Understanding the response mechanism of ecosystem services (ES) to landscape patterns is important in regional landscape planning and sustainable development. In this study, the landscape index and InVEST mode...
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Article
Open AccessThe panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro
Captive pandas are suffering from intestinal infection due to intestinal microbiota characterized by a high abundance of Enterobacteriaceae induced by long-term captivity. Probiotic supplements showed improvement...
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Article
Monocular camera and laser based semantic map** system with temporal-spatial data association for indoor mobile robots
In the future, the goal of service robots is to operate in human-centric indoor environments, requiring close cooperation with humans. In order to enable the robot to perform various interactive tasks, it is n...
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Article
Open AccessPresent geothermal field of the Santos Basin, Brazil
The Santos Basin, located in the southeastern waters of Brazil, is a passive continental margin basin with the most abundant deepwater petroleum resources in the world discovered to date. However, few studies ...
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Chapter and Conference Paper
Research on Remote Sensing Image Object Detection Based on Deep Learning
Remote sensing image has the characteristics of large and complex data volume, which makes the traditional remote sensing image object detection technology difficult to meet the current demand. As artificial i...
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Article
Plastic dissipation of high-capacity electrode materials during lithiation and de-lithiation processes
The plastic deformation of high-capacity anodes during cycling is accompanied by energy dissipation. In certain cases, plastic dissipation can account for a considerable proportion of the total energy dissipat...
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Article
Novel SiC SBD-wall-integrated trench MOSFET with a semi-superjunction and split trench gate
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Article
Synthesis of magnetic nanocomposite Fe3O4@ZIF-8@ZIF-67 and removal of tetracycline in water
We prepared a double-layer magnetic nanocomposite Fe3O4@ZIF-8@ZIF-67 by layer-by-layer self-assembly. Fe3O4@ZIF-8@ZIF-67 was used to remove tetracycline from an aqueous solution via a combination of adsorption an...
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Article
Open AccessAptamer blocking S-TLR4 interaction selectively inhibits SARS-CoV-2 induced inflammation
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Chapter and Conference Paper
Computational Fluid Dynamics Simulation of Cold Spray Process for Particle Velocity Investigation
Computational Fluid Dynamics (CFD) simulation is an effective method to optimize cold spray process parameters and coating quality. The objective of this work is to construct a CFD model to directly investigat...
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Article
Cube sums of the forms 3p and \(3p^2\)
Let \(p\equiv 2,5\ \mathrm {mod}\ 9\) p ≡ 2 ...
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Article
Mystery of methamphetamine-induced autophagosome accumulation in hippocampal neurons: loss of syntaxin 17 in defects of dynein–dynactin driving and autophagosome–late endosome/lysosome fusion
Methamphetamine (METH), a psychoactive-stimulant facilitates massive accumulation of autophagosomes and causes autophagy-associated neuronal death. However, the underlying mechanisms involving METH-induced aut...
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Article
Open AccessUSP39 promotes malignant proliferation and angiogenesis of renal cell carcinoma by inhibiting VEGF-A165b alternative splicing via regulating SRSF1 and SRPK1
The benefit of targeted therapy for renal cell carcinoma (RCC) is largely crippled by drug resistance. Rapid disease progression and poor prognosis occur in patients with drug resistance. New treatments demand...
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Article
Open AccessIntegrating HECW1 expression into the clinical indicators exhibits high accuracy in assessing the prognosis of patients with clear cell renal cell carcinoma
Although many intratumoral biomarkers have been reported to predict clear cell renal cell carcinoma (ccRCC) patient prognosis, combining intratumoral and clinical indicators could predict ccRCC prognosis more ...
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Article
Open AccessThe antiviral activity of kaempferol against pseudorabies virus in mice
Pseudorabies virus (PRV), a member of the Alphaherpesviruses, is one of the most important pathogens that harm the global pig industry. Accumulated evidence indicated that PRV could infect humans under certain ci...
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Article
Open AccessApplication of mediastinal drainage tube in intrathoracic esophageal anastomotic leakage for early diagnosis and effective treatment: a retrospective study
Intrathoracic esophageal anastomotic leakage (AL) is one of the most fatal complications after esophagectomy. In this study, we placed an additional drainage tube in the esophagus bed and evaluated its effect ...
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Article
Open AccessTannins extract from Galla Chinensis can protect mice from infection by Enterotoxigenic Escherichia coli O101
Enterotoxigenic Escherichia coli (ETEC) is classically associated with acute secretory diarrhea, which induces 2 million people death in develo** countries over a year, predominantly children in the first years...