19 Result(s)

Article

China Initiative for Multi-Domain Intervention (CHINA-IN-MUDI) to Prevent Cognitive Decline: Study Design and Progress

Alzheimer’s disease (AD), the most common type of irreversible dementia, is predicted to affect 152 million people by 2050. Evidence from large-scale preventive randomized controlled trials (RCTs) on modifiabl...

S.-Y. Li, X.-Y. **e, D. Liu, G.-R. Cheng… in The Journal of Prevention of Alzheimer's D… (2024)

Article

Effect of Dust Charge Fluctuation on Ion Acoustic Waves in a Plasma with Nonextensive Electrons

The linear dispersion for ion acoustic waves (IAWs) including the effects of dust charge fluctuation and electron nonextensivity is derived. It is shown that the presence of nonextensive electrons modifies the...

X. C. Chen, S. Q. Liu, Y. Liu in Plasma Physics Reports (2019)

Article

Role of Chitosan in the Regulation of the Growth, Antioxidant System and Photosynthetic Characteristics of Maize Seedlings under Cadmium Stress

Cadmium (Cd) pollution was becoming more and more serious; there is an urgent need for an effective solution to inhibit the harm of cadmium stress. Chitosan (CTS) is a biologically active polysaccharide that p...

D. Y. Qu, W. R. Gu, L. G. Zhang, C. F. Li… in Russian Journal of Plant Physiology (2019)

Article

Existence and characterization of Salsolinol synthase in neuronal cells and rat brain

Salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline), the endogenous dopamine-derived catechol isoquinolines whose structure is similar with MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine), m...

X. C. Chen, Y. Chen, G. S. Wu, J. Q. Lu, J. Iqbal, H. Qing… in Neurochemical Journal (2013)

Article

Structure of Cu-Sn Melt at High Temperature

The temperature-dependent viscosity and X-ray diffraction (XRD) patterns of a Cu₆₅Sn₃₅ melt were investigated at high temperatures. The viscosity of the melt changed discontinuously at about 1283 K (1010 °C). An ...

J. X. Hou, C. W. Zhan, X. L. Tian, X. C. Chen… in Metallurgical and Materials Transactions A (2012)

Article

VSV-MP gene therapy strategy inhibits tumor growth in nude mice model of human lung adenocarcinoma

Vesicular stomatitis virus (VSV) matrix protein (MP) can induce in vitro apoptosis of tumor cells in the absence of other viral components. Here, the antitumor activity of VSV-MP against lung adenocarcinoma was i...

X-M **g, Y-J Wen, W Shi, Q-Q Tang, J Li, X-C Chen in Cancer Gene Therapy (2012)

Article

Suppression of ovarian cancer growth via systemic administration with liposome-encapsulated adenovirus-encoding endostatin

Gene therapy using adenoviral vector containing the endostatin gene is a promising strategy for advanced cancers. However, host immune response to adenovirus and the lack of the requisite coxsackie-adenovirus ...

L Yang, L Wang, X-q Su, L Wang, X-c Chen, D Li, S-t Luo, H-s Shi… in Cancer Gene Therapy (2010)

Chapter and Conference Paper

The optimal time-window for surgical treatment of spontaneous intracerebral hemorrhage: result of prospective randomized controlled trial of 500 cases

The aim of this clinical study was to determine the optimal time-window for surgical treatment of spontaneous intracerebral hemorrhage (ICH). From January 1998 to September 2000, 17 hospitals in Shanghai parti...

Y. F. Wang, J. S. Wu, Y. Mao MD, Ph.D, X. C. Chen, L. F. Zhou… in Cerebral Hemorrhage (2008)

Chapter and Conference Paper

Leptin plays a role in ruptured human brain arteriovenous malformations

Intracerebral hemorrhage (ICH) is one of the most common clinical manifestations of human brain arteriovenous malformation (BAVM). However, the hemorrhagic mechanism of BAVM is still unclear. Leptin, first dis...

Q. **e, X. C. Chen, Y. Gong, Y. X. Gu in Cerebral Hemorrhage (2008)

Article

Systemic inhibition of tumor growth by soluble Flk-1 gene therapy combined with cisplatin

Soluble Flk-1, a soluble vascular endothelial growth factor (VEGF) receptor, is a potent inhibitor of angiogenesis, which could restrain growth and metastasis of some experimental tumors. However, antiangiogen...

R Wang, X-W Zhang, G-Q Wang, X-C Chen, L Tian, H-S Yang, M Hu… in Cancer Gene Therapy (2006)

Article

Combination of MIG (CXCL9) chemokine gene therapy with low-dose cisplatin improves therapeutic efficacy against murine carcinoma

MIG (monokine induced by interferon-γ) is a CXC chemokine ligand (CXCL9) that can potently inhibit angiogenesis, and displays thymus-dependent antitumor effects. The effectiveness of a treatment combining gene th...

R Zhang, L Tian, L-J Chen, F **ao, J-M Hou, X Zhao, G Li, B Yao, Y-J Wen… in Gene Therapy (2006)

Article

Protective effect of ginsenoside Rg1 on MPP⁺-induced apoptosis in SHSY5Y cells

 The neuroprotective mechanism of Rg1 was studied in this paper by means of its obvious anti-apoptotic effect on human SHSY5Y cells. SHSY5Y cells were treated with MPP⁺ (1-methyl-4-phenyl-pyridinium) for 72 hours...

X.-C. Chen, F. Fang, Y.-G. Zhu, L.-M. Chen, Y.-C. Zhou… in Journal of Neural Transmission (2003)

Article

CD4 T lymphocytes cause hepatocyte apoptosis by releasing Th1 cytokines in cellular immunological liver injury

Objective and design: To investigate how lymphocytes induce hepatocyte apoptosis.¶Materials and methods: Liver injury was elicited by the trinitrobenzenesulfonic acid (TNBS) in picryl chloride (PCl)-sensitized m...

Q. Xu, X.-C. Chen in Inflammation Research (2002)

Article

Eutectic reaction and microstructural characteristics of Al (Li)-Mg2Si alloys

Thermal analysis, directional solidification and metallographic techniques were applied to investigate the pseudobinary eutectic reaction process and the microstructural characteristics of Al(Li)-Mg₂Si alloys. It...

S.-P. Li, S.-X. Zhao, M.-X. Pan, D.-Q. Zhao, X.-C. Chen… in Journal of Materials Science (2001)

Article

Fabricating TiC particulate reinforced Fe-Cr-Ni matrix composites by a liquid state in-situ synthesis

X. D. Hui, Y. S. Yang, X. C. Chen in Journal of Materials Science Letters (2000)

Article

Solidification of undercooled Ni-32.5 wt% Sn eutectic alloy

Bulk Ni-32.5 wt % Sn alloy was undercooled by purification. The solidification characteristics at different undercoolings and the various microstructures were studied. It was found that the two eutectic phases...

L. Q. **ng, D. Q. Zhao, X. C. Chen in Journal of Materials Science (1993)