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Article
Open AccessMicroRNA-181a-mediated downregulation of AC9 protein decreases intracellular cAMP level and inhibits ATRA-induced APL cell differentiation
AC9 is one of the adenylate cyclase (AC) isoforms, which catalyze the conversion of ATP to cAMP, an important second messenger. We previously found that the integration of cAMP/PKA pathway with nuclear recepto...
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Article
Artificial selection of the melanocortin receptor 1 gene in Chinese domestic pigs during domestication
Black coat colour is common in Chinese indigenous domestic pigs, but not among their wild ancestors, and it is thus presumed to be a ‘domestication trait.’ To determine whether artificial interference contribu...
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Article
The traceability scheme in chemical measurement
Traceability is an essential property of a measurement result. However, it is recognized that the results of chemical measurements can be lacking in this property. In this paper we try to show how to understa...