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  1. No Access

    Article

    Should busulfan therapeutic range be narrowed in pediatrics? Experience from a large cohort of hematopoietic stem cell transplant children

    Busulfan, the corner stone of hematopoietic stem cell transplantation regimens, has a narrow therapeutic window. Therapeutic drug monitoring (TDM)-guided dosing to reach the conventional area under the concent...

    M Philippe, S Goutelle, J Guitton, X Fonrose, C Bergeron… in Bone Marrow Transplantation (2016)

  2. Article

    Open Access

    In vitro hypoxia-conditioned colon cancer cell lines derived from HCT116 and HT29 exhibit altered apoptosis susceptibility and a more angiogenic profile in vivo

    Hypoxia is an important selective force in the clonal evolution of tumours. Through HIF-1 and other transcription factors combined with tumour-specific genetic alterations, hypoxia is a dominant factor in the ...

    K Yao, J A Gietema, S Shida, M Selvakumaran, X Fonrose… in British Journal of Cancer (2005)

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