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Article
Open AccessEnd-of-study safety, immunogenicity, and efficacy of quadrivalent HPV (types 6, 11, 16, 18) recombinant vaccine in adult women 24–45 years of age
Previous analyses from a randomised trial in women aged 24–45 years have shown the quadrivalent human papillomavirus (qHPV) vaccine to be efficacious in the prevention of infection, cervical intraepithelial ne...
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Article
Open AccessEarly age at first sexual intercourse and early pregnancy are risk factors for cervical cancer in develo** countries
Early age at first sexual intercourse (AFSI) has long been associated with an increased risk of invasive cervical carcinoma (ICC). Age at first pregnancy (AFP) and ICC have been investigated less, although AFS...
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Article
Open AccessHPV and cervical cancer: screening or vaccination?
Following the demonstration of the superior validity of human papillomavirus (HPV) tests in screening for cervical cancer and the arrival of highly efficacious HPV 16 and 18 vaccines, cervical cancer preventio...
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Article
Open AccessLifetime body mass index and risk of oral cavity and oropharyngeal cancer by smoking and drinking habits
The influence of body mass index (BMI) on oral cancer risk was evaluated in 375 incident cases and 375 age–gender-matched hospital-based controls. Low BMIs at diagnosis and 2 years before diagnosis were associ...
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Article
Open AccessFood groups and risk of squamous cell carcinoma of the oesophagus: a case–control study in Uruguay
In the time period January 1998–December 2000, a case–control study on squamous cell cancer of the oesophagus was conducted in Montevideo, Uruguay. The main objective of the study was to estimate the odds rati...
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Article
Open AccessPrevalence and determinants of human papillomavirus genital infection in men
Four-hundred-forty-five husbands of women with invasive cervical carcinoma, 165 of women with in situ cervical cancer, and 717 of control women (age range 19–82 years) were interviewed and a sample of exfoliated ...
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Article
Autologous bone marrow transplantation for high risk acute lymphoblastic leukemia: clinical relevance of ex vivo bone marrow purging with monoclonal antibodies and complement
Herein we describe our experience with 75 consecutive autologous BM transplants for patients with high-risk ALL, with special attention to the clinical impact of BM purging. Fifty-two patients received purged ...