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Article
Size-dependent thermomechanical vibration characteristics of rotating pre-twisted functionally graded shear deformable microbeams
A three-dimensional (3D) thermomechanical vibration model is developed for rotating pre-twisted functionally graded (FG) microbeams according to the refined shear deformation theory (RSDT) and the modified cou...
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Article
Open AccessDisease-induced changes in bacterial and fungal communities from plant below- and aboveground compartments
The plant microbes are an integral part of the host and play fundamental roles in plant growth and health. There is evidence indicating that plants have the ability to attract beneficial microorganisms through...
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Article
Open AccessReaction engineering blocks ether cleavage for synthesizing chiral cyclic hemiacetals catalyzed by unspecific peroxygenase
Hemiacetal compounds are valuable building blocks in synthetic chemistry, but their enzymatic synthesis is limited and often hindered by the instability of hemiacetals in aqueous environments. Here, we show th...
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Chapter and Conference Paper
Development and Application of Intelligent Bumper Matching and Sorting System
This paper mainly introduces the intelligent bumper matching and sorting system which has been developed by Dongfeng Nissan in Wuhan factory. Based on the full color difference measurement of robot, the system...
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Article
Open AccessDeciphering cell wall sensors enabling the construction of robust P. pastoris for single-cell protein production
Single-cell protein (SCP) production in the methylotrophic yeast Pichia pastoris has the potential to achieve a sustainable protein supply. However, improving the methanol fermentation efficiency and reducing car...
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Article
Open AccessJMJD6–BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cells
Long non-coding RNA (lncRNA) HOTAIR acts importantly in liver cancer development, but its effect on radioresistance remains poorly understood. Here, our study probed into the possible impact of HOTAIR in radiores...
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Article
Open AccessGelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances
Currently, the clinical treatment of critical bone defects attributed to various causes remains a great challenge, and repairing these defects with synthetic bone substitutes is the most common strategy. In ge...
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Article
Open AccessStudy of the Variables of Local Healthcare Personnel Linked to Becoming a Formal Public CPR Instructor in Baoan, Shenzhen, China
Public Cardiopulmonary resuscitation (CPR) education is important to increase the survival rate of out-of-hospital cardiac arrest (OHCA). In this study, we survey local healthcare personnel in China who met th...
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Article
Role of phosphoenolpyruvate carboxykinase 1 (pck1) in mediating nutrient metabolism in zebrafish
Carbohydrates are the most economical source of energy in fish feeds, but most fish have limited ability to utilize carbohydrates. It has been reported that phosphoenolpyruvate carboxykinase 1 (pck1) is involved ...
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Article
Open AccessRational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles
Chiral heterocyclic compounds are needed for important medicinal applications. We report an in silico strategy for the biocatalytic synthesis of chiral N- and O-heterocycles via Baldwin cyclization modes of hydro...
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Article
DNA methylation of pck1 might contribute to the programming effects of early high-carbohydrate diets feeding to the glucose metabolism across two generations in zebrafish (Danio rerio)
The purpose of this study is to assess the effects of early high-carbohydrate stimulus on glucose metabolism in zebrafish (Danio rerio) over two generations and explore the mechanisms that explain those nutrition...
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Article
Open AccessSuppression of histone deacetylase 1 by JSL-1 attenuates the progression and metastasis of cholangiocarcinoma via the TPX2/Snail axis
Histone deacetylases (HDACs) are entwined with the pathogenesis of various cancers and potentially serve as promising therapeutic targets. Herein, we intend to explore the potential role of HDAC1 inhibitor (JS...
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Article
Open AccessHuman intelectin-1 (ITLN1) genetic variation and intestinal expression
Intelectins are ancient carbohydrate binding proteins, spanning chordate evolution and implicated in multiple human diseases. Previous GWAS have linked SNPs in ITLN1 (also known as omentin) with susceptibility to...
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Article
Open AccessCorrection to: Renal dysfunction reduces the diagnostic and prognostic value of serum CC16 for acute respiratory distress syndrome in intensive care patients
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessRenal dysfunction reduces the diagnostic and prognostic value of serum CC16 for acute respiratory distress syndrome in intensive care patients
Contradictory results regarding changes in serum club cell protein 16 (CC16) levels in patients with acute respiratory distress syndrome (ARDS) have been reported, challenging the value of CC16 as a diagnostic...
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Article
Open AccessPhotobiocatalytic synthesis of chiral secondary fatty alcohols from renewable unsaturated fatty acids
En route to a bio-based chemical industry, the conversion of fatty acids into building blocks is of particular interest. Enzymatic routes, occurring under mild conditions and excelling by intrinsic selectivity...
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Article
Open AccessSilencing of microRNA-135b inhibits invasion, migration, and stemness of CD24+CD44+ pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathway
Recent studies have emphasized determining the ability of microRNAs (miRNAs) as crucial regulators in the occurrence and development of pancreatic cancer (PC), which continues to be one of the deadliest malign...
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Chapter and Conference Paper
A Subjective Assessment Method of Aerospace Image Quality Based on Human Visual System
Aiming at the problems of blur, noise and contrast distortion in aerospace images, a subjective image quality assessment method based on human visual characteristics is proposed in this paper. First, the aeros...
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Article
Open AccessMedroxyprogesterone acetate causes the alterations of endoplasmic reticulum related mRNAs and lncRNAs in endometrial cancer cells
Progestin is effective to promote endometrial cancer (EC) cells apoptosis, however, continuous progestin administration causes low level of progestin receptor B (PRB), further resulting in progestin resistance...
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Article
Effect of welding speed on microstructures and mechanical properties of Al/Cu bimetal composite tubes by a novel friction-based welding process
In this work, a novel friction-based welding technology was developed to weld Al/Cu bimetallic tubes. The macrostructure, microstructure evolutions, and mechanical properties of the joint under different weldi...
