-
Article
Open AccessCholesin receptor signalling is active in cardiovascular system-associated adipose tissue and correlates with SGLT2i treatment in patients with diabetes
Recently deorphanized G protein-coupled receptor 146 (GPR146) was shown to respond to signal from a newly identified hormone—cholesin—and to play a role in hepatic lipid metabolism. However, the importance of ...
-
Article
GlyCulator2: an update on a web application for calculation of glycemic variability indices
-
Article
Open AccessRetinal thickness as a marker of disease progression in longitudinal observation of patients with Wolfram syndrome
Wolfram syndrome (WFS) is a recessively inherited monogenic form of diabetes coexisting with optic atrophy and neurodegenerative disorders with no currently recognized markers of disease progression. The aim o...
-
Article
Open AccessAltered Platelets’ morphological parameters in children with type 1 diabetes – a case-control study
Platelet hyperreactivity is a factor which contributes towards increased risk of cardiovascular events in adults with type 2 diabetes (T2DM). However, little is known about platelets’ disturbances among childr...
-
Article
Open AccessLess but better: cardioprotective lipid profile of patients with GCK-MODY despite lower HDL cholesterol level
Patients with diabetes caused by single-gene mutations generally exhibit an altered course of diabetes. Those with mutations of the glucokinase gene (GCK-MODY) show good metabolic control and low risk of cardiova...
-
Article
Open AccessThree-year comparison of subcutaneous insulin pump treatment with multi-daily injections on HbA1c, its variability and hospital burden of children with type 1 diabetes
Treatment with continuous subcutaneous insulin infusion (CSII) allows a large degree of treatment individualization and intensification in children with diabetes. The study’s aim was to evaluate the impact of ...
-
Article
Open AccessPhenotype variability and neonatal diabetes in a large family with heterozygous mutation of the glucokinase gene
Monogenic diabetes caused by mutations in the glucokinase gene (GCK-MODY) is usually characterized by a mild clinical phenotype. The clinical course of diabetes may be, however, highly variable. The authors pr...