-
Article
Open AccessMolecular fossils in reefal carbonates and sponges of the deep fore reef of Mayotte and Mohéli, Comoro Islands, western Indian Ocean
Microbial carbonates are common components of Quaternary tropical coral reefs. Previous studies revealed that sulfate-reducing bacteria trigger microbial carbonate precipitation in supposedly cryptic reef envi...
-
Article
Open AccessA Randomised Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of Palovarotene Ophthalmic Solution
Palovarotene, a selective retinoic acid receptor γ agonist, is under investigation for the treatment of dry eye disease. This study aimed to determine the ocular and systemic safety, tolerability and pharmacok...
-
Article
Open AccessBioindicators of severe ocean acidification are absent from the end-Permian mass extinction
The role of ocean acidification in the end-Permian mass extinction is highly controversial with conflicting hypotheses relating to its timing and extent. Observations and experiments on living molluscs demonst...
-
Article
A nutrient control on marine anoxia during the end-Permian mass extinction
Oxygen deprivation and hydrogen sulfide toxicity are considered potent kill mechanisms during the mass extinction just before the Permian–Triassic boundary (~251.9 million years ago). However, the mechanism th...
-
Article
Open AccessResilience of marine invertebrate communities during the early Cenozoic hyperthermals
The hyperthermal events of the Cenozoic, including the Paleocene-Eocene Thermal Maximum, provide an opportunity to investigate the potential effects of climate warming on marine ecosystems. Here, we examine th...
-
Article
Open AccessCorrection to: Retinal complications of gout: a case report and review of the literature
After publication of the article [1], it has been brought to our attention that the images displayed in Figs. 1, 2 and 3 have been transposed.
-
Article
Open AccessRetinal complications of gout: a case report and review of the literature
There have been few reported findings of posterior segment complications of gout. While exudative lesions, an increased risk of macular degeneration, and vascular occlusions have been previously reported, to o...
-
Article
Functional diversity of marine ecosystems after the Late Permian mass extinction event
The Late Permian mass extinction event about 252 million years ago was the most severe biotic crisis of the past 500 million years and occurred during an episode of global warming. The loss of around two-third...
