4 Result(s)
within
William C. Parks
English
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Article
Open AccessEpithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection
Epithelial plasticity has been suggested in lungs of mice following genetic depletion of stem cells but is of unknown physiological relevance. Viral infection and chronic lung disease share similar pathologica...
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Article
Open AccessAbnormal respiratory progenitors in fibrotic lung injury
Recent advances in single-cell RNA sequencing (scRNA-seq) and epithelium lineage labeling have yielded identification of multiple abnormal epithelial progenitor populations during alveolar type 2 (ATII) cell d...
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Article
Open AccessEpilysin (matrix metalloproteinase-28) contributes to airway epithelial cell survival
MMP28 is constitutively expressed by epithelial cells in many tissues, including the respiratory epithelium in the lung and keratinocytes in the skin. This constitutive expression suggests that MMP28 may serve...
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Article
Matrix metalloproteinases in lung biology
Despite much information on their catalytic properties and gene regulation, we actually know very little of what matrix metalloproteinases (MMPs) do in tissues. The catalytic activity of these enzymes has been...
