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Article
Open AccessIncreasing pediatric radiation oncology capacity in sub-saharan Africa using technology: a pilot of a pediatric radiation oncology virtual training course
The shortage of skilled healthcare professionals in pediatric oncology and the limited access to training programs remain significant challenges in Nigeria and sub-Saharan Africa. The the Pediatric Radiation O...
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Article
Open AccessPatient reported outcomes following whole brain radiotherapy in patients with brain metastases in NSIA-LUTH Cancer Center
Brain metastases (BM) are a common complication in advanced cancer patients, and extremely challenging to treat. Consequently, whole brain radiotherapy (WBRT) remains the standard palliative intervention for p...
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Article
Modelling treatment-response rates
The time course of tumour responses to immunotherapies can be mathematically predicted on the basis of tumour-growth rates, the rates of immune activation and of tumour–immune-cell interactions, and the effica...
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Article
Systemic immune effects boost radiotherapy
Nanoscale metal–organic frameworks carrying an immunotherapy payload and administered into tumours alongside a low dose of radiotherapy enhance local and systemic antitumour immunity in mouse models of breast ...
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Article
Using immunotherapy to boost the abscopal effect
The abscopal effect, which is the regression of metastatic cancer at distant sites during radiotherapy, is somewhat rare but can be promoted by immunotherapy. This Opinion article describes emerging concepts a...
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Chapter and Conference Paper
Dose enhancement during concomitant chemoradiotherapy using FDA approved concentrations of carboplatin and oxaliplatin nanoparticles
Radiation boosting has been shown in a number of studies to be effective in the prevention of cancer recurrence. To further the effectiveness of this technique, we propose a new method of enhancing dose locall...
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Chapter and Conference Paper
Nanoparticle-aided Radiotherapy for Retinoblastoma and Choroidal Melanoma
This work investigates the dosimetric feasibility of employing gold nanoparticles (AuNPs) or carboplatin nano- particles (CNPs) to enhance radiotherapy (RT) treatment efficacy for ocular cancers: retinoblastom...
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Protocol
Pulsed-Field Gradient-Nuclear Magnetic Resonance (PFG NMR) to Measure the Diffusion of Ions and Polymers in Cartilage
Since cartilage contains neither blood nor lymph vessels, diffusion is the most important transport process for the supply of cartilage with nutrients and for the removal of metabolic waste products. Therefore...