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  1. Article

    Open Access

    Increasing pediatric radiation oncology capacity in sub-saharan Africa using technology: a pilot of a pediatric radiation oncology virtual training course

    The shortage of skilled healthcare professionals in pediatric oncology and the limited access to training programs remain significant challenges in Nigeria and sub-Saharan Africa. The the Pediatric Radiation O...

    Adedayo O. Joseph, Adeseye M. Akinsete, Azeezat O. Ajose in BMC Medical Education (2024)

  2. Article

    Open Access

    Patient reported outcomes following whole brain radiotherapy in patients with brain metastases in NSIA-LUTH Cancer Center

    Brain metastases (BM) are a common complication in advanced cancer patients, and extremely challenging to treat. Consequently, whole brain radiotherapy (WBRT) remains the standard palliative intervention for p...

    Bolanle Adegboyega, Adedayo Joseph, Adewumi Alabi, John Omomila in BMC Cancer (2023)

  3. No Access

    Article

    Modelling treatment-response rates

    The time course of tumour responses to immunotherapies can be mathematically predicted on the basis of tumour-growth rates, the rates of immune activation and of tumour–immune-cell interactions, and the effica...

    Clemens Grassberger, Wilfred Ngwa in Nature Biomedical Engineering (2021)

  4. No Access

    Article

    Systemic immune effects boost radiotherapy

    Nanoscale metal–organic frameworks carrying an immunotherapy payload and administered into tumours alongside a low dose of radiotherapy enhance local and systemic antitumour immunity in mouse models of breast ...

    Wilfred Ngwa in Nature Biomedical Engineering (2018)

  5. No Access

    Article

    Using immunotherapy to boost the abscopal effect

    The abscopal effect, which is the regression of metastatic cancer at distant sites during radiotherapy, is somewhat rare but can be promoted by immunotherapy. This Opinion article describes emerging concepts a...

    Wilfred Ngwa, Omoruyi Credit Irabor, Jonathan D. Schoenfeld in Nature Reviews Cancer (2018)

  6. No Access

    Chapter and Conference Paper

    Dose enhancement during concomitant chemoradiotherapy using FDA approved concentrations of carboplatin and oxaliplatin nanoparticles

    Radiation boosting has been shown in a number of studies to be effective in the prevention of cancer recurrence. To further the effectiveness of this technique, we propose a new method of enhancing dose locall...

    Gizem Cifter, Yucel Altundal, Alex Detappe in World Congress on Medical Physics and Biom… (2015)

  7. No Access

    Chapter and Conference Paper

    Nanoparticle-aided Radiotherapy for Retinoblastoma and Choroidal Melanoma

    This work investigates the dosimetric feasibility of employing gold nanoparticles (AuNPs) or carboplatin nano- particles (CNPs) to enhance radiotherapy (RT) treatment efficacy for ocular cancers: retinoblastom...

    Yucel Altundal, Erno Sajo in World Congress on Medical Physics and Biom… (2015)

  8. No Access

    Protocol

    Pulsed-Field Gradient-Nuclear Magnetic Resonance (PFG NMR) to Measure the Diffusion of Ions and Polymers in Cartilage

    Since cartilage contains neither blood nor lymph vessels, diffusion is the most important transport process for the supply of cartilage with nutrients and for the removal of metabolic waste products. Therefore...

    Jürgen Schiller, Lama Naji, Robert Trampel, Wilfred Ngwa in Cartilage and Osteoarthritis (2004)