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    Article

    Development of microfluidic platform that enables ‘on-chip’ imaging of cells exposed to shear stress and cyclic stretch

    Here, we describe the development of an organ-on-a-chip platform that enables ex vivo studies under active physio-mechanical stress by applying hydrodynamic and mechanical forces to vascular endothelial cells....

    Whitney E. Sinclair, Ashtamurthy S. Pawate in Microfluidics and Nanofluidics (2023)

  2. Article

    Open Access

    Gold nanoparticles disrupt actin organization and pulmonary endothelial barriers

    This study explored the impact of gold nanoparticles on the metabolic activity and morphology of human pulmonary endothelial cell monolayers. We developed a gold nanoparticle library of three different sizes a...

    Whitney E. Sinclair, Huei-Huei Chang, Arkaprava Dan, Paul J. A. Kenis in Scientific Reports (2020)