250 Result(s)
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Open AccessObservation of 2D-magnesium-intercalated gallium nitride superlattices
Since the demonstration of p-type gallium nitride (GaN) through do** with substitutional magnesium (Mg) atoms1,2, rapid and comprehensive developments, such as blue light-emitting diodes, have considerably shap...
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Open AccessTemporal shifts in 24 notifiable infectious diseases in China before and during the COVID-19 pandemic
The coronavirus disease 2019 (COVID-19) pandemic, along with the implementation of public health and social measures (PHSMs), have markedly reshaped infectious disease transmission dynamics. We analysed the im...
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Open AccessIntegrative analysis of metabolomics and transcriptomics to uncover biomarkers in sepsis
To utilize metabolomics in conjunction with RNA sequencing to identify biomarkers in the blood of sepsis patients and discover novel targets for diagnosing and treating sepsis. In January 2019 and December 202...
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Open AccessVisualized in-sensor computing
In artificial nervous systems, conductivity changes indicate synaptic weight updates, but they provide limited information compared to living organisms. We present the pioneering design and production of an el...
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Open AccessRoute planning of mobile robot based on improved RRT star and TEB algorithm
This paper presents a fusion algorithm based on the enhanced RRT* TEB algorithm. The enhanced RRT* algorithm is utilized for generating an optimal global path. Firstly, proposing an adaptive sampling function ...
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Open AccessExcavating important nodes in complex networks based on the heat conduction model
Analyzing the important nodes of complex systems by complex network theory can effectively solve the scientific bottlenecks in various aspects of these systems, and how to excavate important nodes has become a...
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Open AccessAPOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
Several genetic risk factors for Alzheimer’s disease implicate genes involved in lipid metabolism and many of these lipid genes are highly expressed in glial cells1. However, the relationship between lipid metabo...
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Open AccessOxygen-independent organic photosensitizer with ultralow-power NIR photoexcitation for tumor-specific photodynamic therapy
Photodynamic therapy (PDT) is a promising cancer treatment but has limitations due to its dependence on oxygen and high-power-density photoexcitation. Here, we report polymer-based organic photosensitizers (PS...
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Open AccessMulti-omics pan-cancer analyses identify MCM4 as a promising prognostic and diagnostic biomarker
Minichromosome Maintenance Complex Component 4 (MCM4) is a vital component of the mini-chromosome maintenance complex family, crucial for initiating the replication of eukaryotic genomes. Recently, there has b...
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Open AccessEncoding ordered structural complexity to covalent organic frameworks
Installing different chemical entities onto crystalline frameworks with well-defined spatial distributions represents a viable approach to achieve ordered and complex synthetic materials. Herein, a covalent or...
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Open AccessAuthor Correction: Quiescence enables unrestricted cell fate in naive embryonic stem cells
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Open AccessNeuromorphic antennal sensory system
Insect antennae facilitate the nuanced detection of vibrations and deflections, and the non-contact perception of magnetic or chemical stimuli, capabilities not found in mammalian skin. Here, we report a neuro...
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Open AccessMoiré effect enables versatile design of topological defects in nematic liquid crystals
Recent advances in surface-patterning techniques of liquid crystals have enabled the precise creation of topological defects, which promise a variety of emergent applications. However, the manipulation and app...
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Open AccessQuiescence enables unrestricted cell fate in naive embryonic stem cells
Quiescence in stem cells is traditionally considered as a state of inactive dormancy or with poised potential. Naive mouse embryonic stem cells (ESCs) can enter quiescence spontaneously or upon inhibition of M...
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Open AccessObservation of geometric phase effect through backward angular oscillations in the H + HD → H2 + D reaction
Quantum interference between reaction pathways around a conical intersection (CI) is an ultrasensitive probe of detailed chemical reaction dynamics. Yet, for the hydrogen exchange reaction, the difference betw...
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Open AccessDirect in-situ insights into the asymmetric surface reconstruction of rutile TiO2 (110)
The reconstruction of rutile TiO2 (110) holds significant importance as it profoundly influences the surface chemistry and catalytic properties of this widely used material in various applications, from photocata...
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Open AccessSpatial linear transformer and temporal convolution network for traffic flow prediction
Accurately obtaining accurate information about the future traffic flow of all roads in the transportation network is essential for traffic management and control applications. In order to address the challeng...
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Open AccessATP6AP1 as a potential prognostic biomarker in CRC by comprehensive analysis and verification
The role of ATP6AP1 in colorectal cancer (CRC) remains elusive despite its observed upregulation in pan-cancer. Therefore, the current study aimed to assess the clinical significance of ATP6AP1 and its relatio...
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Open AccessDiscovery of lung adenocarcinoma tumor antigens and ferroptosis subtypes for develo** mRNA vaccines
mRNA vaccines are becoming a feasible alternative for treating cancer. To develop mRNA vaccines against LUAD, potential antigens were identified and LUAD ferroptosis subtypes distinguished for selecting approp...
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Open AccessPig-eRNAdb: a comprehensive enhancer and eRNA dataset of pigs
Enhancers and the enhancer RNAs (eRNAs) have been strongly implicated in regulations of transcriptions. Based the multi-omics data (ATAC-seq, ChIP-seq and RNA-seq) from public databases, Pig-eRNAdb is a datase...