-
Article
Open AccessGenetic analysis of 42 Y-STR loci in Han and Manchu populations from the three northeastern provinces in China
Y-STR polymorphisms are useful in tracing genealogy and understanding human origins and migration history. This study aimed to fill a knowledge gap in the genetic diversity, structure, and haplogroup distribut...
-
Article
Differential bone remodeling mechanism in hindlimb unloaded and hibernating Daurian ground squirrels: a comparison between artificial and natural disuse within the same species
Loss of bone mass can occur in mammals after prolonged disuse but the situation for hibernators that are in a state of torpor for many months of the year is not yet fully understood. The present study assesses...
-
Article
Open AccessSHANK2 is a frequently amplified oncogene with evolutionarily conserved roles in regulating Hippo signaling
Dysfunction of the Hippo pathway enables cells to evade contact inhibition and provides advantages for cancerous overgrowth. However, for a significant portion of human cancer, how Hippo signaling is perturbed...
-
Article
Author Correction: Hormones induce the formation of luminal-derived basal cells in the mammary gland
In the initial published version of this article, there was a mistake in one author name (**gsong Li). The correct name should be “**song Li”. This correction does not affect the description of the results o...
-
Article
Hormones induce the formation of luminal-derived basal cells in the mammary gland
In the mammary gland, it is widely believed that the luminal cells are unipotent after birth, contributing only to the luminal compartment in normal development. Here, by lineage tracing, we uncovered an unexp...
-
Article
Open AccessIdentification of blood vascular endothelial stem cells by the expression of protein C receptor
Vascular growth and remodeling are dependent on the generation of new endothelial cells from stem cells and the involvement of perivascular cells to maintain vessel integrity and function. The existence and ce...
-
Article
Open AccessN-Acetylgalactosaminyltransferase-14 as a potential biomarker for breast cancer by immunohistochemistry
The post-translational modification of proteins, including glycosylation, differs between normal and tumor cells. The UDP-N-acetyl-D-galactosamine polypeptide N-acetylgalactosaminyltransferases (GalNAc-Tases) ...
-
Article
GalNAc-T14 may be involved in regulating the apoptotic action of IGFBP-3
Insulin-like growth factor binding protein-3 (IGFBP-3) is known to induce apoptosis in an insulin-like growth factor (IGF)-dependent and IGF-independent manner, but the mechanism underlying the IGF-independent...
