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Article
Targeting androgen receptor phase separation to overcome antiandrogen resistance
Patients with castration-resistant prostate cancer inevitably acquire resistance to antiandrogen therapies in part because of androgen receptor (AR) mutations or splice variants enabling restored AR signaling....
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Chapter
Experimental Methods Used for Identifying Small-Molecule Inhibitors of Protein-Protein Interaction
Protein-protein interactions (PPIs) are implicated innumerous biological processes under physiological and pathophysiological conditions. They thus offer new opportunities for therapeutic intervention. Various...