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    Article

    Targeting androgen receptor phase separation to overcome antiandrogen resistance

    Patients with castration-resistant prostate cancer inevitably acquire resistance to antiandrogen therapies in part because of androgen receptor (AR) mutations or splice variants enabling restored AR signaling....

    **g**g **e, Hao He, Wenna Kong, Ziwen Li, Zhenting Gao in Nature Chemical Biology (2022)

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    Experimental Methods Used for Identifying Small-Molecule Inhibitors of Protein-Protein Interaction

    Protein-protein interactions (PPIs) are implicated innumerous biological processes under physiological and pathophysiological conditions. They thus offer new opportunities for therapeutic intervention. Various...

    Mi Zhou, Qing Li, Wenna Kong, Renxiao Wang in Targeting Protein-Protein Interactions by … (2018)