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Article
Open AccessThe roles of tissue resident macrophages in health and cancer
As integral components of the immune microenvironment, tissue resident macrophages (TRMs) represent a self-renewing and long-lived cell population that plays crucial roles in maintaining homeostasis, promoting...
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Article
Open AccessAdvancements of radiotherapy for recurrent head and neck cancer in modern era
Head and neck cancer is a kind of cancer which can be eradicated from radical radiation therapy. However, with best efforts, nearly 40% patients will experience locoregional recurrence. Locoregional recurrence...
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Article
Open AccessTargeted co-delivery of curcumin and erlotinib by MoS2 nanosheets for the combination of synergetic chemotherapy and photothermal therapy of lung cancer
Curcumin (Cur), a bioactive component of Chinese traditional medicine, has demonstrated inhibitory properties against cancer cell proliferation while synergistically enhancing the anticancer efficacy of erloti...
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Article
Dissipation, residue, and dietary risk assessment of dimethachlon in grapes
Dimethachlon, a dicarboximide fungicide, has gained widespread usage in Asian countries. While considered a low-toxicity fungicide, concerns regarding potential health effects, such as nephrotoxicity, have eme...
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Article
Based on the IWATE criteria: to investigate the influence of different surgical approaches on the perioperative outcomes of hepatectomy
In terms of perioperative outcomes, compared with traditional open surgery and laparoscopic surgery, studies of robotic liver resection have been limited and must be further clarified.
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Chapter and Conference Paper
Advancing Delineation of Gross Tumor Volume Based on Magnetic Resonance Imaging by Performing Source-Free Domain Adaptation in Nasopharyngeal Carcinoma
Nasopharyngeal carcinoma (NPC) is a common and significant malignancy that primarily affects the head and neck region. Accurate delineation of Gross Tumor Volume (GTV) is crucial for effective radiotherapy in ...
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Chapter and Conference Paper
Scribble-Based 3D Multiple Abdominal Organ Segmentation via Triple-Branch Multi-Dilated Network with Pixel- and Class-Wise Consistency
Multi-organ segmentation in abdominal Computed Tomography (CT) images is of great importance for diagnosis of abdominal lesions and subsequent treatment planning. Though deep learning based methods have attain...
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Article
Metabolic signatures of hepatolithiasis using ultra-high performance liquid chromatography-tandem mass spectrometry
A metabolomic study of hepatolithiasis has yet to be performed. The purpose of the present study was to characterize the metabolite profile and identify potential biomarkers of hepatolithiasis using a metabolo...
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Article
Open AccessNCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN
NCAPG, non-SMC subunit in the concentrate I complex, might promote the proliferation of hepatocellular carcinoma (HCC), but the mechanism is unclear. The aim of this study was to explore how NCAPG affects PTEN...
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Article
Open AccessCirculating long non-coding RNA TTTY15 and HULC serve as potential novel biomarkers for predicting acute myocardial infarction
Acute myocardial infarction (AMI) is a ubiquitous cardiovascular disease ensuing adverse prognosis caused by myocardial necrosis. Effective and rapid diagnosis of AMI is essential to following treatment in cli...
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Chapter and Conference Paper
Scribble-Supervised Medical Image Segmentation via Dual-Branch Network and Dynamically Mixed Pseudo Labels Supervision
Medical image segmentation plays an irreplaceable role in computer-assisted diagnosis, treatment planning and following-up. Collecting and annotating a large-scale dataset is crucial to training a powerful seg...
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Article
Open AccessModified median hepatic fissure approach for resection of liver tumours located in the angle between the root of the middle and right hepatic veins
Liver tumours between the root angle of the middle and right hepatic veins are a special type of liver segment VIII tumour. In this study, we designed a modified median hepatic fissure approach to remove these...
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Article
Open AccessA novel dosimetric metrics-based risk model to predict local recurrence in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy
To develop a risk model based on dosimetric metrics to predict local recurrence in nasopharyngeal carcinoma (NPC) patients treated with intensive modulated radiation therapy (IMRT).
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Article
Open AccessWhole-exome sequencing reveals the etiology of the rare primary hepatic mucoepidermoid carcinoma
Primary hepatic mucoepidermoid carcinoma (HMEC) is extremely rare and the molecular etiology is still unknown. The CRTC1-MAML2 fusion gene was previously detected in a primary HMEC, which is often associated with...
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Chapter and Conference Paper
Efficient Semi-supervised Gross Target Volume of Nasopharyngeal Carcinoma Segmentation via Uncertainty Rectified Pyramid Consistency
Gross Target Volume (GTV) segmentation plays an irreplaceable role in radiotherapy planning for Nasopharyngeal Carcinoma (NPC). Despite that Convolutional Neural Networks (CNN) have achieved good performance f...
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Article
Open AccessGastrointestinal mixed adenoneuroendocrine carcinoma: a population level analysis of epidemiological trends
The rise in incidence and mortality of gastrointestinal mixed adenoneuroendocrine carcinoma (MANEC) has not been well focused. The aim of our study was to examine epidemiological trends in incidence and incide...
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Article
The Phytopathogenic Fungus Pallidocercospora crystallina-Caused Localized Subcutaneous Phaeohyphomycosis in a Patient with a Homozygous Missense CARD9 Mutation
In the past decade, an increasing number of otherwise healthy individuals suffered from invasive fungal infections due to inherited CARD9 mutations. Herein, we present a patient with a homozygous CARD9 mutation w...
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Article
Open AccessNon-functional pancreatic neuroendocrine tumours: emerging trends in incidence and mortality
Our aim was to determine the epidemiology and recent changes in the trends of non-functional pancreatic neuroendocrine tumours (NF-pNETs) at the population level. In addition, we explored the risk factors that...
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Article
Open AccessTime-restricted feeding causes irreversible metabolic disorders and gut microbiota shift in pediatric mice
Time-restricted feeding regimen (TRF), that is, no food consumption for 14–16 h during the light phase per day, attenuates the fattening traits and metabolic disorders in adults. This study aims to further inv...
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Article
Open AccessCombined hepatocellular-cholangiocarcinoma: a population level analysis of incidence and mortality trends
The purpose of this study was to explore trends in incidence, incidence-based (IB) mortality, and survival for combined hepatocellular-cholangiocarcinoma (cHCC-CC) utilizing a population-based database to attr...
