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Article
C9orf72 controls hepatic lipid metabolism by regulating SREBP1 transport
Sterol regulatory element binding transcription factors (SREBPs) play a crucial role in lipid homeostasis. They are processed and transported to the nucleus via COPII, where they induce the expression of lipog...
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Article
Experimental Study of Alkali-Activated Slag Crushed Aggregate Blocks During and After Exposure to Elevated Temperatures
Nowadays, significant research effort is being dedicated to explore environmentally friendly block materials with high strength and high-temperature resistance. Ground-granulated blast-furnace slag (GGBFS) is ...
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Article
Study on the shear behaviour of steel–concrete composite beams after elevated temperature and water cooling
The study of the mechanical behaviour of steel–concrete composite beams under fire is of great importance. However, little attention has been paid to the effect of elevated temperatures on the shear performanc...
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Article
Open AccessU-shaped association between serum 25-hydroxyvitamin D concentrations and urinary leakage among adult females aged 45 years and over in the United States: a cross-sectional study
The relationship between serum vitamin D status and urinary leakage (UL) among middle-aged females needs to be further studied. The aim of this study was to evaluate the association of serum 25-hydroxyvitamin ...
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Article
General Prediction Models for Local Bearing Capacity of Concrete
The local bearing capacity is a basic mechanical property, which is crucial in the post-tensioned anchorage zone design. However, it is challenging to accurately predict local bearing capacity due to the disor...
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Article
Anchorage zone behavior and strength prediction of high-performance concrete containing coarse aggregate confined with spirals
High-performance concrete containing coarse aggregate (HPC-CA) has superior cost efficiency and reduced early cracking risk compared with traditional UHPC. HPC-CA is distinguished by high strength, lightweight...
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Article
Seismic performance of concrete columns confined by high-strength stirrups
The concrete columns confined by high-strength stirrups exhibited higher bearing capacity and better deformation ability. Based on the test results of concrete columns confined by high-strength stirrups under ...
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Article
The functional coupling between restriction and DNA phosphorothioate modification systems underlying the DndFGH restriction complex
Bacteria have evolved diverse mechanisms to cope with the constant threat of phage predation. DndABCDE-catalysed DNA phosphorothioate modification, in which the non-bridging oxygen of the DNA sugar-phosphate b...
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Article
Compressive strength evaluation of concrete confined with spiral stirrups by using adaptive neuro-fuzzy inference system (ANFIS)
The compressive strength of concrete confined with spiral stirrups was an important parameter to evaluate the load-bearing capacity of concrete columns. The confinement provided by spiral stirrups let concrete...
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Article
Seismic behavior of full-scale RC columns jacketed by modified multi-spiral stirrups
The purpose of this study was to investigate the seismic behavior of RC columns jacketed with a large welded octagonal stirrup at the center and four small spiral stirrups at the corners. Six full-scale RC col...
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Article
Experiment and validation of local bearing capacity for reactive powder concrete confined with high-strength spirals
In this study, ten reactive powder concrete (RPC) specimens confined by high-strength spirals loaded over a limited area are used to investigate their behaviour and determine their local bearing capacity. The ...
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Article
Compression behavior of ultra-high performance concrete (UHPC) confined with high-strength rectilinear ties
To explore the compression behavior of ultra-high-performance concrete (UHPC) confined with rectilinear ties, sixty specimens were tested under axial compression. The investigated parameters included the compr...
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Article
Effect of fibre dosage and stress-strength ratio on creep of polypropylene fibre-reinforced alkali-activated slag concrete
The use of alkali-activated slag (AAS), an eco-friendly cementitious material, to replace ordinary Portland cement in construction can reduce the energy consumption, CO2 emissions, and solid dust pollution and pr...
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Article
Lateral dilation and limited value of volumetric ratio of stirrups for ultra-high strength concrete confined with spiral stirrups
Ultra-high strength concrete (UHSC) has high compressive strength and tends to fail in brittle under axial compression. The lateral confinements of spiral stirrups can be significantly enhanced the ductility o...
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Article
Lateral response of HPC confined by both spiral stirrups and CFRP under axial compression
Lateral response is the lateral expansion deformation of confined concrete under axial compression which is used as an indicator to evaluate the lateral confinements of confining materials. In this paper, an a...
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Article
Open AccessMulti-omics analysis of tumor angiogenesis characteristics and potential epigenetic regulation mechanisms in renal clear cell carcinoma
Tumor angiogenesis, an essential process for cancer proliferation and metastasis, has a critical role in prognostic of kidney renal clear cell carcinoma (KIRC), as well as a target in guiding treatment with an...
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Article
Experimental investigation of full-scale concrete columns confined by high-strength transverse reinforcement subjected to lateral cyclic loading
The use of high-strength longitudinal and transverse reinforcements in confined concrete columns can improve bearing capacity and deformability. Besides, experiments on confined concrete columns with side leng...
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Article
Quantifying Fire Insulation Effects on the Fire Response of Hybrid-Fiber Reinforced Reactive Powder Concrete Beams
The fire performance of reinforced reactive powder concrete (RPC) beams has raised much concern due to the sensitivity of these beams to high temperature and relatively lower fire resistance. To achieve the fi...
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Article
Open AccessEffects of Temperature and Stress on Creep Behavior of PP and Hybrid Fiber Reinforced Reactive Powder Concrete
Reactive powder concrete (RPC) is an advanced cementitious material with ultra-high strength, remarkable durability and excellent toughness. However, temperature dependent creep is a major concern as very litt...
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Article
Serum Alpha1-Globulin as a Novel Prognostic Factor in Metastatic Renal Cell Carcinoma Treated with Tyrosine Kinase Inhibitors
Serum protein fraction (SPF) is a common parameter reflecting the nutritional and inflammatory status of the human body. However, its role in patients with cancer, particularly those treated with targeted agen...
