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Article
Characterization of a novel recombinant NADC30‑like porcine reproductive and respiratory syndrome virus in Shanxi Province, China
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important pathogens affecting the swine industry. In this report, a novel PRRSV strain SXht2012 was isolated from Shanxi province ...
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Article
Open AccessEnhanced potency of an IgM-like nanobody targeting conserved epitope in SARS-CoV-2 spike N-terminal domain
Almost all the neutralizing antibodies targeting the receptor-binding domain (RBD) of spike (S) protein show weakened or lost efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerg...
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Article
Generation of a live attenuated influenza A vaccine by proteolysis targeting
The usefulness of live attenuated virus vaccines has been limited by suboptimal immunogenicity, safety concerns or cumbersome manufacturing processes and techniques. Here we describe the generation of a live a...
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Article
Open AccessTranscriptome-based biomarker gene screening and evaluation of the extracellular fatty acid-binding protein (Ex-FABP) on immune and angiogenesis-related genes in chicken erythrocytes of tibial dyschondroplasia
Tibial dyschondroplasia (TD) is a bone disorder in which dead chondrocytes accumulate as a result of apoptosis and non-vascularization in the tibial bone of broiler chickens. The pathogenicity of TD is under e...
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Physiology of Endocrine System and Related Metabolic Disorders
Endocrine system is comprised of multiple glands. All of these glands secrete different hormones into the body. Most of the body’s functions, i.e., metabolism, growth, development, electrolyte balance, and rep...
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Article
Open AccessTranscriptome-based screening of intracellular pathways and angiogenesis related genes at different stages of thiram induced tibial lesions in broiler chickens
The Tibial dyschondroplasia (TD) in fast-growing chickens is mainly caused by improper blood circulation. The exact mechanism underlying angiogenesis and vascularization in tibial growth plate of broiler chick...
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Chapter
Analytical Techniques for the Assessment of Drug Stability
The expansion of the medications fetched an upheaval in the human healthcare system. These medicines would assist their role only when they do not have any contamination and being administered in the desired q...
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Article
Open AccessTranscripts of antibacterial peptides in chicken erythrocytes infected with Marek’s disease virus
Chicken erythrocytes are involved in immunity through binding of toll-like receptors (TLRs) with their ligands to activate downstream signaling and lead to cytokine production in erythrocytes. Some avian β-def...
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Article
Open AccessScreening of differentially expressed genes in the growth plate of broiler chickens with Tibial Dyschondroplasia by microarray analysis
Tibial dyschondroplasia (TD) is a common skeletal disorder in broiler chickens. It is characterized by the presence of a non-vascularized and unmineralized cartilage in the growth plate. Previous studies have ...
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Article
Polymorphisms in chicken extracellular fatty acid binding protein gene
In this study, we report the investigation of extracellular fatty acid binding protein gene (Ex-FABP) genetic polymorphism in a sample of 360 chicken individuals. The screening of the coding regions with their in...
