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  1. Article

    Open Access

    Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation

    Cellular senescence frequently occurs during anti-cancer treatment, and persistent senescent tumor cells (STCs) unfavorably promote tumor progression through paracrine secretion of the senescence-associated se...

    Dan Zhang, Jian-Wei Zhang, Hui Xu, **n Chen, Yu Gao, Huan-Gang Jiang in Molecular Cancer (2024)

  2. No Access

    Article

    Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization

    Keloid is a benign skin tumor characterized by its cell hyperproliferative activity, invasion into normal skin, uncontrolled growth, overproduction and deposition of extracellular matrices and high recurrence ...

    Bo-ya Zhou, Wen-bo Wang, **ao-li Wu, Wen-jie Zhang in Acta Pharmacologica Sinica (2020)

  3. Article

    Preparation, characterization, in vivo and in vitro studies of arsenic trioxide Mg-Fe ferrite magnetic nanoparticles

    MgFe2O4 magnetic nanoparticle composed of As2O3 (As2O3-MNPs) were prepared and their in vitro and in vivo characteristics were studied.

    Guo-fu Yang, **ang-hui Li, Zhe Zhao, Wen-bo Wang in Acta Pharmacologica Sinica (2009)