15 Result(s)
within
Wen-Yih Isaac Tseng
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Article
Open AccessDevelopmental change of brain volume in Rett syndrome in Taiwan
Rett syndrome (RTT) is characterized by neurological regression. This pioneering study investigated the effect of age on brain volume reduction by analyzing magnetic resonance imaging findings in participants ...
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Open AccessAdvanced brain aging in Parkinson’s disease with cognitive impairment
Patients with Parkinson’s disease and cognitive impairment (PD-CI) deteriorate faster than those without cognitive impairment (PD-NCI), suggesting an underlying difference in the neurodegeneration process. We ...
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Open AccessThe microstructural change of the brain and its clinical severity association in pediatric Tourette syndrome patients
Gilles de la Tourette syndrome (GTS) is a prevalent pediatric neurological disorder. Most studies point to abnormalities in the cortico-striato-thalamocortical (CSTC) circuits. Neuroimaging studies have shown ...
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Neurodevelopmental model of schizophrenia revisited: similarity in individual deviation and idiosyncrasy from the normative model of whole-brain white matter tracts and shared brain-cognition covariation with ADHD and ASD
The neurodevelopmental model of schizophrenia is supported by multi-level impairments shared among schizophrenia and neurodevelopmental disorders. Despite schizophrenia and typical neurodevelopmental disorders...
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Article
Open AccessBrain white matter correlates of learning ankle tracking using a wearable device: importance of the superior longitudinal fasciculus II
Wearable devices have been found effective in training ankle control in patients with neurological diseases. However, the neural mechanisms associated with using wearable devices for ankle training remain larg...
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Article
ADHD symptoms map onto noise-driven structure–function decoupling between hub and peripheral brain regions
Adults with childhood-onset attention-deficit hyperactivity disorder (ADHD) show altered whole-brain connectivity. However, the relationship between structural and functional brain abnormalities, the implicati...
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Open AccessCorrelation of dystonia severity and iron accumulation in Rett syndrome
Individuals with Rett syndrome (RTT) commonly demonstrate Parkinsonian features and dystonia at teen age; however, the pathological reason remains unclear. Abnormal iron accumulation in deep gray matter were r...
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Article
Boys with autism spectrum disorder have distinct cortical folding patterns underpinning impaired self-regulation: a surface-based morphometry study
Although impaired self-regulation (dysregulation) in autism spectrum disorder (ASD) garnered increasing awareness, the neural mechanism of dysregulation in ASD are far from conclusive. To complement our previo...
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Article
Open AccessUltrastructural and diffusion tensor imaging studies reveal axon abnormalities in Pompe disease mice
Pompe disease (PD) is caused by lysosomal glycogen accumulation in tissues, including muscles and the central nervous system (CNS). The intravenous infusion of recombinant human acid alpha-glucosidase (rhGAA) ...
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Article
Open AccessAssociation of self-regulation with white matter correlates in boys with and without autism spectrum disorder
Previous studies demonstrated distinct neural correlates underpinning impaired self-regulation (dysregulation) between individuals with autism spectrum disorder (ASD) and typically develo** controls (TDC). H...
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Article
Phase-contrast magnetic resonance imaging for analyzing hemodynamic parameters and wall shear stress of pulmonary arteries in patients with pulmonary arterial hypertension
To investigate flow-related parameters in pulmonary arteries of patients with pulmonary arterial hypertension (PAH).
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Article
Open AccessDevelopment of frontoparietal connectivity predicts longitudinal symptom changes in young people with autism spectrum disorder
Structural neuroimaging studies suggest altered brain maturation in autism spectrum disorder (ASD) compared with typically develo** controls (TDC). However, the prognostic value of whole-brain structural con...
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Article
Open AccessRegional brain volume differences between males with and without autism spectrum disorder are highly age-dependent
Neuroanatomical differences between individuals with and without autism spectrum disorder (ASD) were inconsistent in the literature. Such heterogeneity may substantially originate from age-differential effects.
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Article
A Vision for Translating Neuroimaging Techniques into Clinical Applications through Collaboration
Through the advancement of non-invasive neuroimaging techniques, functional brain imaging research has gained widespread acceptance and increased clinical applications. In Taiwan, similar advances are also eme...
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Chapter
Diffusion Magnetic Resonance Imaging in Neuroimaging
Diffusion is one of the basic phenomena in nature and can be quantified with magnetic resonance imaging (MRI) in terms of signal attenuation. Diffusion MRI portrays the geometry of microstructures based on the...
