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  1. Article

    Open Access

    Disentangling the syntrophic electron transfer mechanisms of Candidatus geobacter eutrophica through electrochemical stimulation and machine learning

    Interspecies hydrogen transfer (IHT) and direct interspecies electron transfer (DIET) are two syntrophy models for methanogenesis. Their relative importance in methanogenic environments is still unclear. Our r...

    Heyang Yuan, Xuehao Wang, Tzu-Yu Lin, **ha Kim, Wen-Tso Liu in Scientific Reports (2021)

  2. Article

    Open Access

    Ecology and molecular targets of hypermutation in the global microbiome

    Changes in the sequence of an organism’s genome, i.e., mutations, are the raw material of evolution. The frequency and location of mutations can be constrained by specific molecular mechanisms, such as diversi...

    Simon Roux, Blair G. Paul, Sarah C. Bagby, Stephen Nayfach in Nature Communications (2021)

  3. Article

    Open Access

    Catabolism and interactions of uncultured organisms shaped by eco-thermodynamics in methanogenic bioprocesses

    Current understanding of the carbon cycle in methanogenic environments involves trophic interactions such as interspecies H2 transfer between organotrophs and methanogens. However, many metabolic processes are th...

    Masaru K. Nobu, Takashi Narihiro, Ran Mei, Yoichi Kamagata, Patrick K. H. Lee in Microbiome (2020)

  4. Article

    Open Access

    Machine learning-aided analyses of thousands of draft genomes reveal specific features of activated sludge processes

    Microorganisms in activated sludge (AS) play key roles in the wastewater treatment processes. However, their ecological behaviors and differences from microorganisms in other environments have mainly been stud...

    Lin Ye, Ran Mei, Wen-Tso Liu, Hongqiang Ren, Xu-**ang Zhang in Microbiome (2020)

  5. Article

    Open Access

    Quantifying the contribution of microbial immigration in engineered water systems

    Immigration is a process that can influence the assembly of microbial communities in natural and engineered environments. However, it remains challenging to quantitatively evaluate the contribution of this pro...

    Ran Mei, Wen-Tso Liu in Microbiome (2019)

  6. Article

    Open Access

    Diversity and geochemical community assembly processes of the living rare biosphere in a sand-and-gravel aquifer ecosystem in the Midwestern United States

    Natural microbial communities consist of a limited number of abundant species and an extraordinarily diverse population of rare species referred to as the rare biosphere. Recent studies have revealed that the ...

    Kyosuke Yamamoto, Keith C. Hackley, Walton R. Kelly, Samuel V. Panno in Scientific Reports (2019)

  7. Article

    Open Access

    Coupling growth kinetics modeling with machine learning reveals microbial immigration impacts and identifies key environmental parameters in a biological wastewater treatment process

    Ubiquitous in natural and engineered ecosystems, microbial immigration is one of the mechanisms sha** community assemblage. However, quantifying immigration impact remains challenging especially at individua...

    Ran Mei, **ha Kim, Fernanda P. Wilson, Benjamin T. W. Bocher, Wen-Tso Liu in Microbiome (2019)

  8. Article

    Correction: Corrigendum: Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

    Nat. Biotechnol. 35, 725–731 (2017); published online 8 August 2017; corrected after print 29 November 2017; corrected after print 7 December 2017 In the version of this article initially published, the author...

    Robert M Bowers, Nikos C Kyrpides, Ramunas Stepanauskas in Nature Biotechnology (2018)

  9. Article

    Open Access

    Effect of divalent ions and a polyphosphate on composition, structure, and stiffness of simulated drinking water biofilms

    The biofilm chemical and physical properties in engineered systems play an important role in governing pathogen transmission, fouling facilities, and corroding metal surfaces. Here, we investigated how simulat...

    Yun Shen, Pin Chieh Huang, Conghui Huang, Peng Sun in npj Biofilms and Microbiomes (2018)

  10. Article

    Open Access

    Ugly ducklings—the dark side of plastic materials in contact with potable water

    Bath toys pose an interesting link between flexible plastic materials, potable water, external microbial and nutrient contamination, and potentially vulnerable end-users. Here, we characterized biofilm communi...

    Lisa Neu, Carola Bänziger, Caitlin R. Proctor, Ya Zhang in npj Biofilms and Microbiomes (2018)

  11. Article

    Correction: Corrigendum: Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

    Nat. Biotechnol. 35, 725–731 (2017); published online 8 August 2017; corrected after print 29 November 2017; corrected after print 7 December 2017 In the version of this article initially published, the follow...

    Robert M Bowers, Nikos C Kyrpides, Ramunas Stepanauskas in Nature Biotechnology (2018)

  12. Article

    Open Access

    Diverse Marinimicrobia bacteria may mediate coupled biogeochemical cycles along eco-thermodynamic gradients

    Microbial communities drive biogeochemical cycles through networks of metabolite exchange that are structured along energetic gradients. As energy yields become limiting, these networks favor co-metabolic inte...

    Alyse K. Hawley, Masaru K. Nobu, Jody J. Wright, W. Evan Durno in Nature Communications (2017)

  13. Article

    Open Access

    Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

    Standards for sequencing the microbial 'uncultivated majority', namely bacterial and archaeal single-cell genome sequences, and genome sequences from metagenomic datasets, are proposed.

    Robert M Bowers, Nikos C Kyrpides, Ramunas Stepanauskas in Nature Biotechnology (2017)

  14. No Access

    Article

    Direct treatment of high-strength soft drink wastewater using a down-flow hanging sponge reactor: performance and microbial community dynamics

    A stand-alone down-flow hanging sponge (DHS) system with a two-stage configuration was operated for 700 days to treat synthetic soft drink wastewater at 3000 mg/L chemical oxygen demand (COD). Throughout the o...

    Junhui Liao, Curtis Fang, Jimmy Yu in Applied Microbiology and Biotechnology (2017)

  15. Article

    Open Access

    Evaluating digestion efficiency in full-scale anaerobic digesters by identifying active microbial populations through the lens of microbial activity

    Anaerobic digestion is a common technology to biologically stabilize wasted solids produced in municipal wastewater treatment. Its efficiency is usually evaluated by calculating the reduction in volatile solid...

    Ran Mei, Takashi Narihiro, Masaru K. Nobu, Kyohei Kuroda, Wen-Tso Liu in Scientific Reports (2016)

  16. Article

    Open Access

    XXIV World Allergy Congress 2015

    A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts

    Heung-Man Lee, Il-Ho Park, Jae-Min Shin in World Allergy Organization Journal (2016)

  17. No Access

    Article

    Global metabolomic responses of Nitrosomonas europaea 19718 to cold stress and altered ammonia feeding patterns

    The model ammonia-oxidizing bacterium Nitrosomonas europaea represents one of the environmentally and biotechnologically significant microorganisms. Genome-based studies over the last decade have led to many intr...

    Huijie Lu, Alexander V. Ulanov, Masaru Nobu in Applied Microbiology and Biotechnology (2016)

  18. No Access

    Article

    Effects of hydraulic retention time on aerobic granulation and granule growth kinetics at steady state with a fast start-up strategy

    A hydraulic retention time (HRT) of 4, 6, and 8 h was employed, respectively, in three reactors to study the effects of HRT on granulation with a newly developed fast granulation strategy, i.e., a strategy by ...

    Yong-Qiang Liu, **ng Zhang, Rui Zhang in Applied Microbiology and Biotechnology (2016)

  19. No Access

    Reference Work Entry In depth

    The Family Dermatophilaceae

    The family Dermatophilaceae embraces Gram-positive, high G+C, facultative anaerobic or strictly aerobic chemoorganotrophic bacteria with a wide range of habitats such as animal and human skin, fish guts, and wast...

    Konstantina Kagia, Wen-Tso Liu in The Prokaryotes (2014)

  20. Article

    Open Access

    Insights into the phylogeny and coding potential of microbial dark matter

    Genome sequencing enhances our understanding of the biological world by providing blueprints for the evolutionary and functional diversity that shapes the biosphere. However, microbial genomes that are current...

    Christian Rinke, Patrick Schwientek, Alexander Sczyrba, Natalia N. Ivanova in Nature (2013)

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