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Article
Open AccessYAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions
Maladaptive repair of acute kidney injury (AKI) is associated with a high risk of develo** chronic kidney disease deemed irremediable even in present days. When AKI arises from ischemia-reperfusion injury, h...
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Article
Open AccessThe HLTF–PARP1 interaction in the progression and stability of damaged replication forks caused by methyl methanesulfonate
Human HLTF participates in the lesion-bypass mechanism through the fork reversal structure, known as template switching of post-replication repair. However, the mechanism by which HLTF promotes the replication...
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Article
Correction: Src and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration
The original version of this article contained error in Fig. 6b, where several panels were missing from the published version. The corrected version of this Figure now appears in the article.
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Article
Open AccessSrc and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration
Vimentin intermediate filaments (VIFs), expressed in most mesenchymal and cancer cells, undergo dramatic reorganization during cell migration; however, the mechanism remains obscure. This study demonstrates th...
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Article
Open AccessBcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis
Ca2+ plays a significant role in linking the induction of apoptosis. The key anti-apoptotic protein, Bcl-2, has been reported to regulate the movement of Ca2+ across the ER membrane, but the exact effect of Bcl-2...