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  1. Article

    Open Access

    YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions

    Maladaptive repair of acute kidney injury (AKI) is associated with a high risk of develo** chronic kidney disease deemed irremediable even in present days. When AKI arises from ischemia-reperfusion injury, h...

    Heng-Ai Chang, Rui-Zhi Ou Yang, **g-Ming Su, Thi My Hang Nguyen in Cell Death Discovery (2023)

  2. Article

    Open Access

    The HLTF–PARP1 interaction in the progression and stability of damaged replication forks caused by methyl methanesulfonate

    Human HLTF participates in the lesion-bypass mechanism through the fork reversal structure, known as template switching of post-replication repair. However, the mechanism by which HLTF promotes the replication...

    Jia-Lin Shiu, Cheng-Kuei Wu, Song-Bin Chang, Yan-Jhih Sun, Yen-Ju Chen in Oncogenesis (2020)

  3. Article

    Correction: Src and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration

    The original version of this article contained error in Fig. 6b, where several panels were missing from the published version. The corrected version of this Figure now appears in the article.

    Cheng-Yi Yang, Po-Wei Chang, Wen-Hsin Hsu, Hsuan-Chia Chang, Chien-Lin Chen in Oncogene (2019)

  4. Article

    Open Access

    Src and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration

    Vimentin intermediate filaments (VIFs), expressed in most mesenchymal and cancer cells, undergo dramatic reorganization during cell migration; however, the mechanism remains obscure. This study demonstrates th...

    Cheng-Yi Yang, Po-Wei Chang, Wen-Hsin Hsu, Hsuan-Chia Chang, Chien-Lin Chen in Oncogene (2019)

  5. Article

    Open Access

    Bcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis

    Ca2+ plays a significant role in linking the induction of apoptosis. The key anti-apoptotic protein, Bcl-2, has been reported to regulate the movement of Ca2+ across the ER membrane, but the exact effect of Bcl-2...

    Wen-Tai Chiu, Heng-Ai Chang, Yi-Hsin Lin, Yu-Shan Lin in Cell Death Discovery (2018)