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  1. Article

    Open Access

    RNA structure profiling at single-cell resolution reveals new determinants of cell identity

    RNA structure is critical for multiple steps in gene regulation. However, how the structures of transcripts differ both within and between individual cells is unknown. Here we develop a SHAPE-inspired method c...

    Jiaxu Wang, Yu Zhang, Tong Zhang, Wen Ting Tan, Finnlay Lambert in Nature Methods (2024)

  2. Article

    Publisher Correction: Determination of isoform-specific RNA structure with nanopore long reads

    A Correction to this paper has been published: https://doi.org/10.1038/s41587-021-00889-5.

    Jong Ghut Ashley Aw, Shaun W. Lim, Jia Xu Wang in Nature Biotechnology (2021)

  3. Article

    Author Correction: Determination of isoform-specific RNA structure with nanopore long reads

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Jong Ghut Ashley Aw, Shaun W. Lim, Jia Xu Wang in Nature Biotechnology (2021)

  4. No Access

    Article

    Determination of isoform-specific RNA structure with nanopore long reads

    Current methods for determining RNA structure with short-read sequencing cannot capture most differences between distinct transcript isoforms. Here we present RNA structure analysis using nanopore sequencing (...

    Jong Ghut Ashley Aw, Shaun W. Lim, Jia Xu Wang in Nature Biotechnology (2021)

  5. Article

    Open Access

    β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development

    β-defensin family plays a role in host defense against viral infection, however its role in HCV infection is still unknown. In this study, we demonstrated that β-defensin 1 was significantly reduced in HCV-inf...

    Yue-Ming Ling, **-Yu Chen, Libin Guo, Chen-Yi Wang, Wen-Ting Tan in Scientific Reports (2017)