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  1. Article

    Open Access

    Nitric oxide mediates red light-induced perylenequinone production in Shiraia mycelium culture

    Perylenequinones (PQs) from bambusicolous Shiraia fungi serve as excellent photosensitizers for photodynamic therapy. However, the lower yield of PQ production in mycelium cultures is an important bottleneck for ...

    Wen Juan Wang, **n ** Li, Wen Hao Shen, Qun Yan Huang in Bioresources and Bioprocessing (2024)

  2. No Access

    Article

    Bamboo polysaccharides elicit hypocrellin A biosynthesis of a bambusicolous fungus Shiraia sp. S9

    Hypocrellin A (HA), a fungal perylenequinone from bambusicolous Shiraia species, is a newly developed photosensitizer for photodynamic therapy in cancer and other infectious diseases. The lower yield of HA is an ...

    Wen Hao Shen, Lu Lu Zhou, **n ** Li in World Journal of Microbiology and Biotechn… (2023)

  3. Article

    Open Access

    Effects of branched-chain amino acids on Shiraia perylenequinone production in mycelium cultures

    Perylenequinones from Shiraia fruiting bodies are excellent photosensitizers and widely used for anti-cancer photodynamic therapy (PDT). The lower yield of Shiraia perylenequinones becomes a significant bottlenec...

    Wen Hao Shen, Rui Peng Cong, **n ** Li, Qun Yan Huang in Microbial Cell Factories (2023)

  4. Article

    Open Access

    Contrasting regulation of live Bacillus cereus No.1 and its volatiles on Shiraia perylenequinone production

    Fungal perylenequinones (PQs) are a class of photoactivated polyketide mycotoxins produced by plant-associated fungi. Hypocrellins, the effective anticancer photodynamic therapy (PDT) agents are main bioactive...

    Rui Xu, **n ** Li, **ang Zhang, Wen Hao Shen, Chun Yan Min in Microbial Cell Factories (2022)

  5. No Access

    Article

    Analysis of chemical compounds and toxicological evaluation of Forsythia suspensa leaves tea

    To determine the compositions of Forsythia suspensa leaves tea (FSLT) and its safety, the chemical compounds were analysed with some methods, and the toxicity was evaluated in Kunming mice and Wistar rats. The re...

    Da-Hong Wang, Meng-Yang Wang, Wen-Hao Shen in Food Science and Biotechnology (2021)

  6. No Access

    Article

    Preparation and Characterization of TiO2 Nanotube Arrays with Short Tube Length and Its Photocatalytic Degradation of Organic Pollutants

    In this study, highly ordered TiO2 nanotube arrays (TNAs) with length 1~2 μm were rapidly fabricated via the electrochemical anodic oxidation process, which was specifically used for the photocatalytic degradatio...

    Jiao Li, Wen-hao Shen, Shu-fang Song, **ao-quan Chen in Water, Air, & Soil Pollution (2020)

  7. No Access

    Article

    Increased SPHK1 expression is associated with poor prognosis in bladder cancer

    Upregulation of sphingosine kinase 1 (SPHK1) protein has been reported to be associated with a poor prognosis in a variety of malignant tumors. However, the role of SPHK1 in bladder cancer (BC) has not been th...

    **ao-Dong Meng, Zhan-Song Zhou, Jian-Hong Qiu, Wen-Hao Shen, Qu Wu in Tumor Biology (2014)

  8. No Access

    Article

    Association of BLCA-4 Hypomethylation in Blood Leukocyte DNA and the Risk of Bladder Cancer in a Chinese Population

    Global DNA hypomethylation has been associated with increased risk for cancers of the colorectum, bladder, breast, head and neck, and testicular germ cells. The aim of this study was to examine whether global ...

    Hui-**ang Ji, Qian Zhao, **-Hong Pan, Wen-Hao Shen in Pathology & Oncology Research (2013)

  9. No Access

    Article

    Distribution, development and proliferation of interstitial cells of Cajal in murine colon: an immunohistochemical study from neonatal to adult life

    This paper aimed at investigating the alterations in interstitial cells of Cajal (ICC) in the proximal, middle and distal colon of mice from 0-day to 56-day post-partum (P0–P56) by immunohistochemistry. The Kit+ ...

    Juan Han, Wen-Hao Shen, You-Zhao Jiang, Bin Yu in Histochemistry and Cell Biology (2010)

  10. No Access

    Article

    Flow mixing model of liquid phase in an internal airlift loop reactor

    Residence time distribution (RTD) analysis of liquid phase was conducted in an internal airlift loop reactor (AL) and a bubble column (BC) with the tracer response technique. These data were simulated and comp...

    Da-shi Nie, Wen-hao Shen, Qun-jiao Liu in Journal of Shanghai University (English Ed… (2006)