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  1. No Access

    Article

    Genetic and clinical characteristics of acute B-cell lymphoblastic leukemia with MEF2D fusions and report of two novel MEF2D rearrangements

    The MEF2D rearrangement is a recurrent chromosomal abnormality detected in approximately 2.4–5.3% of patients with acute B-cell lymphoblastic leukemia (B-ALL). Currently, MEF2D-rearranged B-ALL is not classified ...

    Han-Yu Cao, Hui-Ying Li, Wen-Zhi Cai, Yuan-Hong Huang in Annals of Hematology (2024)

  2. Article

    Open Access

    Dual-modal radiomics nomogram based on contrast-enhanced ultrasound to improve differential diagnostic accuracy and reduce unnecessary biopsy rate in ACR TI-RADS 4–5 thyroid nodules

    American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TI-RADS, TR) 4 and 5 thyroid nodules (TNs) demonstrate much more complicated and overlap** risk characteristics than TR1-3 and h...

    Jia-Yu Ren, Wen-Zhi Lv, Liang Wang, Wei Zhang, Ying-Ying Ma in Cancer Imaging (2024)

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    Article

    PD-L1 antibody enhanced β-glucan antitumor effects via blockade of the immune checkpoints in a melanoma model

    In the tumor microenvironment (TME), one of the major functions of tumor-recruited CD11b+ cells are the suppression of the T-cell-mediated anti-tumor immune response. β-glucan could convert the phenotype of tumor...

    **n Hu, Yifang Shui, Hiroshi Hirano, Kisato Kusano in Cancer Immunology, Immunotherapy (2023)

  4. Article

    Open Access

    Immune checkpoint inhibitors in the treatment of virus-associated cancers

    Among all malignant tumors that threaten human health, virus-related tumors account for a large proportion. The treatment of these tumors is still an urgent problem to be resolved. The immune system is the “gu...

    Peipei Gao, Cordelle Lazare, Canhui Cao, Yifan Meng in Journal of Hematology & Oncology (2019)

  5. No Access

    Article

    MiR-34c inhibits osteosarcoma metastasis and chemoresistance

    Studies have shown that miR-34c is associated with metastasis and the chemoresponse of several cancers, but its role in osteosarcoma (OS) is unclear. Here, we investigated the role and mechanism of miR-34c i...

    Meng Xu, Hua **, Cheng-**ong Xu, Wen-Zhi Bi, Yan Wang in Medical Oncology (2014)

  6. No Access

    Article

    Magnetic resonance imaging is appropriate for determining the osteotomy plane for appendicular osteosarcoma after neoadjuvant chemotherapy

    There are no standard criteria for determining a sufficient resection margin in the treatment of osteosarcoma. The purposes of this study are to evaluate clinical outcomes using T1-weighted magnetic resonance ...

    Gang Han, Yan Wang, Wen-Zhi Bi, Dian-Jun Wang, Shi-Bi Lu, Li Zhang in Medical Oncology (2012)

  7. No Access

    Article

    Hepatic Angiomyolipoma: A Clinical Experience in Diagnosis and Treatment

    Hepatic angiomyolipoma is a rare mesenchyme-derived neoplasm often misdiagnosed as hepatocellular carcinoma, and the treatment for it remains controversial.

    Jian-** Zeng, Jia-Hong Dong, Wen-Zhi Zhang, **g Wang in Digestive Diseases and Sciences (2010)

  8. No Access

    Article

    Extracorporeal high intensity focused ultrasound treatment for patients with breast cancer

    Purpose. To investigate the safety, efficacy and feasibility of using high-intensity focused ultrasound (HIFU) as a non-invasive treatment for patients with breast cancer.

    Feng Wu, Zhi-Biao Wang, Hui Zhu, Wen-Zhi Chen in Breast Cancer Research and Treatment (2005)

  9. No Access

    Article

    Extracorporeal High Intensity Focused Ultrasound Ablation in the Treatment of Patients with Large Hepatocellular Carcinoma

    Background: High intensity focused ultrasound (HIFU) is a noninvasive treatment modality that induces complete coagulative necrosis of a deep tumor through the intact skin. The current st...

    Feng Wu MD, PhD, Zhi-Biao Wang MD, PhD, Wen-Zhi Chen MD in Annals of Surgical Oncology (2004)