59 Result(s)
within
Wen** Peng
Life Sciences
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Article
Open AccessSETDB1 regulates short interspersed nuclear elements and chromatin loop organization in mouse neural precursor cells
Transposable elements play a critical role in maintaining genome architecture during neurodevelopment. Short Interspersed Nuclear Elements (SINEs), a major subtype of transposable elements, are known to harbor...
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Article
Effects of an anti-WSSV transgenic cyanobacterial oral agent on the development, reproduction, and physiology of Daphnia magna
Trans-vp28 gene cyanobacteria have good efficacy as an oral agent against shrimp white spot syndrome virus (WSSV) infection in shrimp and have promising applications. However, little research on the environmental...
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Open AccessTherapeutic targeting of ARID1A-deficient cancer cells with RITA (Reactivating p53 and inducing tumor apoptosis)
ARID1A, a component of the SWI/SNF chromatin-remodeling complex, is frequently mutated in various cancer types and has emerged as a potential therapeutic target. In this study, we observed that ARID1A-deficien...
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Genomic data and ecological niche modeling reveal an unusually slow rate of molecular evolution in the Cretaceous Eupteleaceae
Living fossils are evidence of long-term sustained ecological success. However, whether living fossils have little molecular changes remains poorly known, particularly in plants. Here, we have introduced a nov...
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Open AccessComparative plastome analysis of the sister genera Ceratocephala and Myosurus (Ranunculaceae) reveals signals of adaptive evolution to arid and aquatic environments
Expansion and contraction of inverted repeats can cause considerable variation of plastid genomes (plastomes) in angiosperms. However, little is known about whether structural variations of plastomes are assoc...
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Open AccessTREM2 macrophage promotes cardiac repair in myocardial infarction by reprogramming metabolism via SLC25A53
Efferocytosis and metabolic reprogramming of macrophages play crucial roles in myocardial infarction (MI) repair. TREM2 has been proven to participate in phagocytosis and metabolism, but how it modulates myoca...
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Open AccessThe ZJU index is associated with the risk of obstructive sleep apnea syndrome in Chinese middle-aged and older people: a cross-sectional study
The ZJU index, a novel calculation that combines body mass index, triglycerides, fasting blood glucose and the ratio of alanine aminotransferase to aspartate aminotransferase, is a closely related measure of o...
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In vitro adventitious regeneration and plantlet transplantation of Atractylodes chinensis (DC.) Koidz., a valuable medicinal plant
Triploid Atractylodes chinensis (DC.) Koidz. is a valuable genetic resource for medicinal plant breeding, and there is a demand to develop an efficient in vitro regeneration protocol to resolve triploid sterility...
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Article
Open AccessPrematurely delivering mothers show reductions of lachnospiraceae in their gut microbiomes
Preterm birth is the leading cause of perinatal morbidity and mortality. Despite evidence shows that imbalances in the maternal microbiome associates to the risk of preterm birth, the mechanisms underlying the...
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Application of AtMYB75 as a reporter gene in the study of symbiosis between tomato and Funneliformis mosseae
Composite plants containing transgenic hairy roots produced with Agrobacterium rhizogenes-mediated transformation have become an important method to study the interaction between plants and arbuscular mycorrhizal...
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Article
Use of terrestrial laser scanning to obtain the stem diameters of Larix olgensis and construct compatible taper-volume equations
Using Hough transform to extract the stem diameter from TLS data to relative height of 0.7, the established compatible taper-volume equations was able to accurately estimate the stem volume.
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Open AccessGBC: a parallel toolkit based on highly addressable byte-encoding blocks for extremely large-scale genotypes of species
Whole -genome sequencing projects of millions of subjects contain enormous genotypes, entailing a huge memory burden and time for computation. Here, we present GBC, a toolkit for rapidly compressing large-scal...
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Article
A convenient, reliable and directly visual selection marker for identifying transgenic lines of Solanum nigrum
Solanum nigrum L. is an annual herb of Solanaceae and Solanum genus. S. nigrum has not been domesticated. S. nigrum produces a small, spherical, black, highly nutritious edible fruit. To achieve the potential of ...
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Open AccessLoss of TET2 impairs endothelial angiogenesis via downregulating STAT3 target genes
Ischemic diseases represent a major global health care burden. Angiogenesis is critical in recovery of blood flow and repair of injured tissue in ischemic diseases. Ten–eleven translocation protein 2 (TET2), a...
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Article
Acetylation licenses Th1 cell polarization to constrain Listeria monocytogenes infection
T helper 1 (Th1) immunity is typically viewed as a critical adaptation by vertebrates against intracellular pathogens. Identifying novel targets to enhance Th1 cell differentiation and function is increasingly...
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Open AccessARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination
Ariadne homolog 2 (ARIH2) is a key member of the RING-between-RING (RBR) E3 ligase family, which is characterized by an RBR domain involved in the polyubiquitination process. However, the molecular mechanism a...
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Article
Extracellular vesicles derived from human Sertoli cells: characterizations, proteomic analysis, and miRNA profiling
Extracellular vesicles (EVs) contain thousands of proteins and nucleic acids, playing an important role in cell–cell communications. Sertoli cells have been essential in the testis as a “nurse cell”. However, ...
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Isolation and genomic analysis of temperate phage 5W targeting multidrug-resistant Acinetobacter baumannii
Temperate phages are potential therapeutic agents, but only a few temperate phages infecting multidrug-resistant Acinetobacter baumannii have been identified. In this study, we isolated 5W, a temperate phage that...
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Changes of Community Structure and Functional Feeding Groups of Benthic Macrofauna After Mangrove Afforestation in a Subtropical Intertidal Zone, China
Afforestation is a primary response to the loss and degradation of mangroves worldwide. The successful restoration of mangrove ecosystems is in part indicated by the rebuilding of macrobenthic community. Howev...
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Construction and application of easy-to-detect cyanobacteria with vp28 gene
White Spot Syndrome Virus (WSSV) is the most harmful and pathogenic infectious agent in shrimp aquaculture. Vp28, a protein used to protect hosts against this virus, has successfully been expressed in nine hos...
