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Article
Open AccessCorrection: Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer
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Article
Open AccessEpigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer
Human epidermal growth factor receptor 2 (HER2)-amplified breast cancers are treated using targeted antibodies and kinase inhibitors, but resistance to these therapies leads to systemic tumor recurrence of metast...
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Article
Open AccessBiased signaling downstream of epidermal growth factor receptor regulates proliferative versus apoptotic response to ligand
Inhibition of epidermal growth factor receptor (EGFR) signaling by small molecule kinase inhibitors and monoclonal antibodies has proven effective in the treatment of multiple cancers. In contrast, metastatic ...