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Article
Treatment of cytokine release syndrome-induced vascular endothelial injury using mesenchymal stem cells
Cytokine release syndrome (CRS) is an acute systemic inflammatory reaction in which hyperactivated immune cells suddenly release a large amount of cytokines, leading to exaggerated inflammatory responses, mult...
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Article
Open AccessMeta-analysis on last ten years of clinical injection of bone marrow-derived and umbilical cord MSC to reverse cirrhosis or rescue patients with acute-on-chronic liver failure
Recent studies have shown that mesenchymal stem cell (MSC) therapy has potential therapeutic effects for patients with end-stage liver diseases. However, a consensus on the efficacy and safety of MSCs has not ...
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Article
Open AccessImmune and cytokine alterations and RNA-sequencing analysis in gestational tissues from pregnant women after recovery from COVID-19
COVID-19 is a global pandemic. Understanding the immune responses in pregnant women recovering from COVID-19 may suggest new therapeutic approaches.
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Article
Open AccessEquatorial Pacific dust fertilization and source weathering influences on Eocene to Miocene global CO2 decline
Stimulation of the biological pump by iron-bearing dust in the eastern equatorial Pacific Ocean plays an important role in long-term carbon sequestration, yet past dust fertilization and its impact on CO2 perturb...
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Article
Open AccessMesenchymal stem/stromal cell therapy for COVID-19 pneumonia: potential mechanisms, current clinical evidence, and future perspectives
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread into more than 200 countries and infected approximately 203 million people g...
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Article
Open AccessHuman umbilical cord mesenchymal stem cell promotes angiogenesis via integrin β1/ERK1/2/HIF-1α/VEGF-A signaling pathway for off-the-shelf breast tissue engineering
Mesenchymal stem cells (MSC)-based tissue engineered breast represent the visible future for breast reconstruction after mastectomy. However, autologous MSCs might not be appropriate for the large graft constr...
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Article
Open AccessRs12976445 polymorphism is associated with the risk of post-SAH re-bleeding by modulating the expression of microRNA-125 and ET-1
This study aimed to study the association between rs12976445 polymorphism and the incidence of IA re-bleeding. Genotype and allele frequency analysis was performed to study the association between rs12976445 p...
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Article
Initial rifting process and dynamics mechanism of Huaguang Sag: Evidence from a numerical modeling method
Huaguang Sag is located in the deep seawater area of Qiongdongnan Basin, and its tectonic position belongs to the intersection of NE-trending, SN-trending and NW-trending tectonic systems in the continental ma...
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Article
ARF triggers cell G1 arrest by a P53 independent ERK pathway
In this study, in order to investigate the p53-independent function of p14ARF, we established p14ARF-inducible clones in the p53-deficient HCT cell line using the doxycycline-inducible expression system. A str...
