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Article
Gsdma3 is a new factor needed for TNF-α-mediated apoptosis signal pathway in mouse skin keratinocytes
Gsdma3, a newly found gene, is expressed restrictedly in mouse skin keratinocytes and gastrointestinal tract. But until now, there is little information on the regulation and the function of Gsdm...
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Article
SCF/c-kit signaling is required in 12-O-tetradecanoylphorbol-13-acetate-induced migration and differentiation of hair follicle melanocytes for epidermal pigmentation
Hair follicle melanocyte stem cells (McSCs) are responsible for hair pigmentation and also function as a major melanocyte reservoir for epidermal pigmentation. However, the molecular mechanism promoting McSCs ...
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Article
Prolonged overexpression of Wnt10b induces epidermal keratinocyte transformation through activating EGF pathway
Wnt10b is a signaling protein regulating skin development and homeostasis, and the expression of Wnt10b is restricted to epidermal keratinocytes in embryonic and postnatal skin. Recent studies indicate an elevate...
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Article
Hoxc13 is a crucial regulator of murine hair cycle
Hair follicles undergo cyclical growth and regression during postnatal life. Hair regression is an apoptosis-driven process strictly controlled by micro- and macro-environmental signals. However, how these sig...
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Article
12-O-tetradecanoylphorbol-13-acetate activates hair follicle melanocytes for hair pigmentation via Wnt/β-catenin signaling
Melanocyte stem cells (McSCs) undergo cyclical activation and quiescence together with hair follicle stem cells (HFSCs). This process is strictly controlled by the autonomous and extrinsic signaling environmen...
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Article
Hair follicle stem cell proliferation, Akt and Wnt signaling activation in TPA-induced hair regeneration
Regeneration of hair follicles relies on activation of hair follicle stem cells during telogen to anagen transition process in hair cycle. This process is rigorously controlled by intrinsic and environmental f...
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Protocol
Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro
Coordinated regeneration of melanocyte stem cells (McSCs) and hair follicle stem cells (HSCs) contributes to generation of pigmented hairs. Synchronous regeneration of McSCs with activation of HSCs occurs not ...
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Article
A new dynamic culture device suitable for rat skin culture
Cultured skin has been used extensively for testing therapeutic drugs because it replicates the physical and biochemical properties of whole skin. However, traditional static culture cannot fully maintain cell...
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Article
Touchscreen tags based on thin-film electronics for the Internet of Everything
Capacitive touchscreens are increasingly widespread, featuring in mobile phones and tablets, as well as everyday objects such as cars and home appliances. As a result, the interfaces are uniquely placed to pro...
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Article
Electrically assisted amplified spontaneous emission in perovskite light-emitting diodes
Metal halide perovskites have emerged as promising gain materials for thin-film laser diodes. However, achieving electrically excited amplified spontaneous emission (ASE) in perovskite light-emitting diodes (P...