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  1. Article

    Open Access

    Prediction of various insulin resistance indices for the risk of hypertension among military young adults: the CHIEF cohort study, 2014–2020

    Non-insulin-based insulin resistance (NI-IR) indices have been reported to have an association with prevalent hypertension, however, no cohort studies to date have compared their prediction of hypertension amo...

    Kun-Zhe Tsai, Chen-Chih Chu, Wei-Chun Huang, Xuemei Sui in Cardiovascular Diabetology (2024)

  2. Article

    Open Access

    Localized periodontitis severity associated with carotid intima-media thickness in young adults: CHIEF atherosclerosis study

    This study aimed to investigate the association of periodontitis with subclinical atherosclerosis in young adults. In total, 486 non-diabetic military personnel were included in Taiwan. Carotid intima-media th...

    Kun-Zhe Tsai, Wei-Chun Huang, Yun-Chen Chang, Younghoon Kwon in Scientific Reports (2023)

  3. No Access

    Chapter and Conference Paper

    Evaluation of Recurrent Neural Network Model Training for Health Care Suggestions

    Neural networks have revolutionized the field of data analytics and decision support, where recurrent neural networks are designed for solving time-series data. Total care is a synonym for complete patient car...

    Ming-Hsia Hsu, Wang-Chuan Juang in 2021 International Conference on Security … (2023)

  4. Article

    Open Access

    Using real-time visualization system for data-driven decision support to achieve lung protective strategy: a retrospective observational study

    Although lung protective strategy and adjunctive intervention are associated with improved survival in patients with acute respiratory distress syndrome (ARDS), the implementation of effective therapies remain...

    How-Yang Tseng, Chieh-Lung Chen, Yu-Chao Lin, Ming-Che Chuang, Wu-Huei Hsu in Critical Care (2022)

  5. Article

    Open Access

    Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis

    Post-resuscitation hemodynamic level is associated with outcomes. This study was conducted to investigate if post-resuscitation diastolic blood pressure (DBP) is a favorable prognostic factor.

    Chien-Yu Chi, Min-Shan Tsai, Li-Kuo Kuo, Hsin-Hui Hsu in Journal of Intensive Care (2022)

  6. Article

    Open Access

    Sex-specific cardiometabolic risk markers of left ventricular mass in physically active young adults: the CHIEF heart study

    Greater physical fitness may lead to greater left ventricular mass (LVM) and reduce the effect of cardiometabolic risk factors on LVM. However, the cardiometabolic biomarkers associations for LVM have not been...

    Kun-Zhe Tsai, Pang-Yen Liu, Wei-Chun Huang, Joao A. C. Lima in Scientific Reports (2022)

  7. Article

    Open Access

    Selective and predicable amine conjugation sites by kinetic characterization under excess reagents

    The site selectivity for lysine conjugation on a native protein is difficult to control and characterize. Here, we applied mass spectrometry to examine the conjugation kinetics of Trastuzumab-IgG (Her-IgG) and...

    Wei-Chun Huang, Li-Juan Huang, Liang-Sheng Hsu, Shih-Ting Huang in Scientific Reports (2021)

  8. No Access

    Article

    Develo** an Integrated Electronic Medication Reconciliation Platform and Evaluating its Effects on Preventing Potential Duplicated Medications and Reducing 30-Day Medication-Related Hospital Revisits for Inpatients

    The aims were to develop an integrated electronic medication reconciliation (ieMR) platform, evaluate its effects on preventing potential duplicated medications, analyze the distribution of the potential dupli...

    Pi-Lien Hung, Pei-Chin Lin, Jung-Yi Chen, Miao-Ting Chen in Journal of Medical Systems (2021)

  9. No Access

    Article

    Comparison of effects of triple antithrombotic therapy and dual antiplatelet therapy on long-term outcomes of acute myocardial infarction

    Warfarin is an alternate choice for patients who are not eligible for non-vitamin K oral anticoagulants after acute myocardial infarction (AMI). This study aimed to compare the long-term outcome of triple anti...

    Mei-Tzu Wang, Cheng Chung Hung, Kun-Chang Lin, Guang-Yuan Mar in Heart and Vessels (2021)

  10. Article

    Open Access

    Inhibition of Neointima Hyperplasia, Inflammation, and Reactive Oxygen Species in Balloon-Injured Arteries by HVJ Envelope Vector-Mediated Delivery of Superoxide Dismutase Gene

    Extracellular superoxide dismutase (EC-SOD) has been implicated in regulation of vascular function but its underlying molecular mechanism is largely unknown. These two-step experiments investigate whether hema...

    Shoa-Lin Lin, Jwu-Lai Yeh, Pei-Chia Tsai in Translational Stroke Research (2019)

  11. No Access

    Article

    Improving outcomes in chronic obstructive pulmonary disease by taking beta-blockers after acute myocardial infarction: a nationwide observational study

    β-Blockers are a standard therapy for acute myocardial infarction (AMI) due to their better short-term and long-term outcomes. However, β-blockers are often under-prescribed in chronic obstructive pulmonary di...

    Wen-Hwa Wang, Chin-Chang Cheng, Guang-Yuan Mar, Kai-Che Wei in Heart and Vessels (2019)

  12. Article

    Open Access

    De-escalation from ticagrelor to clopidogrel in acute coronary syndrome patients: a systematic review and meta-analysis

    De-escalation from ticagrelor to clopidogrel in acute coronary syndrome (ACS) may occur for a variety of reasons, including side effects (bleeding and non-bleeding) and costs. This study sought to assess the p...

    Dominick J. Angiolillo, Giuseppe Patti in Journal of Thrombosis and Thrombolysis (2019)

  13. Article

    Open Access

    Combination Therapy with Dipyridamole and Clopidogrel for Secondary Stroke Prevention in Aspirin-Intolerant Patients After Myocardial Infarction: Results of a Nationwide Case-Control Study

    Combination therapy with dipyridamole and clopidogrel in stroke prevention and long-term outcomes in aspirin-intolerant patients with acute myocardial infarction (AMI) and previous stroke are unknown. This nat...

    Mei-Tzu Wang, Hsin-Li Liang, Cheng Chung Hung, Pei-Ling Tang, Kun-Chang Lin in CNS Drugs (2019)

  14. Article

    Open Access

    Pneumocystis jirovecii pneumonia in HIV-uninfected, rituximab treated non-Hodgkin lymphoma patients

    Rituximab is associated with a higher incidence of Pneumocystis jirovecii pneumonia infection. Pneumocystis prophylaxis is advised in many immunocompromised populations treated with rituximab. However, the benefi...

    Kai-Che Wei, Chenglen Sy, Shang-Yin Wu, Tzu-Jung Chuang in Scientific Reports (2018)

  15. Article

    Open Access

    Propensity score analysis of lung cancer risk in a population with high prevalence of non-smoking related lung cancer

    Lung cancer has been the leading cause of cancer-related mortality worldwide among both men and women in recent years. There is an increase in the incidence of nonsmoking-related lung cancer in recent years. T...

    Kuei-Feng Lin, Hsiu-Fu Wu, Wei-Chun Huang, Pei-Ling Tang in BMC Pulmonary Medicine (2017)

  16. Article

    Analysis of gallstone disease after gastric cancer surgery

    The incidence rate of newly developed gallstone disease after gastrectomy for gastric cancer is thought to be higher than that in the general population. However, the presentation and management of these galls...

    Tsung-Jung Liang, Shiuh-Inn Liu, Yu-Chia Chen, Po-Min Chang in Gastric Cancer (2017)

  17. Article

    Open Access

    The impact of DPP-4 inhibitors on long-term survival among diabetic patients after first acute myocardial infarction

    Previous studies regarding the cardioprotective effects of dipeptidyl peptidase 4 (DPP-4) inhibitors have not provided sufficient evidence of a relationship between DPP-4 inhibition and actual cardiovascular o...

    Mei-Tzu Wang, Sheng-Che Lin, Pei-Ling Tang, Wang-Ting Hung in Cardiovascular Diabetology (2017)

  18. Article

    Open Access

    Differential hemodynamic characteristics of high-resistance vs. high-flow type of pulmonary artery hypertension revealed by phase-contrast MRI

    Ming-Ting Wu, Chen-Hua Wang in Journal of Cardiovascular Magnetic Resonan… (2015)

  19. No Access

    Article

    Detection of coronary artery disease using real-time myocardial contrast echocardiography: a comparison with dual-isotope resting thallium-201/stress technectium-99m sestamibi single-photon emission computed tomography

    Real-time myocardial contrast echocardiography (MCE) has the potential to evaluate myocardial perfusion and wall motion (WM) simultaneously. The purposes of this study were to correlate the diagnostic value of...

    Shoa-Lin Lin, Kuan-Rau Chiou, Wei-Chun Huang, Nan-**g Peng in Heart and Vessels (2006)

  20. No Access

    Article

    Efficacy and safety of statins in hypercholesterolemia with emphasis on lipoproteins

    Information of the effect of statin on lipoproteins such as apolipoprotein (apo) A-I, lipoprotein (a) [Lp (a)], or apolipoprotein B levels is limited. This investigation was a crossover study designed to evalu...

    San-Chiang Wu, Jeng-Chuan Shiang, Shoa-Lin Lin, Te-Lang Wu in Heart and Vessels (2005)