-
Article
Open AccessCharacteristics of intermediate age-related macular degeneration with hyperreflective foci
Hyperreflective foci (HRF) are the findings observed in optical coherence tomography (OCT) in several retinal diseases and are believed to be associated with the increased risk of atrophy in eyes with age-rela...
-
Article
Open AccessDistinct characteristics of central serous chorioretinopathy according to gender
To investigate the differences in clinical and genetic characteristics between males and females with central serous chorioretinopathy (CSC). Consecutive 302 patients (mean age; 56.3 ± 11.7, male/female: 249/5...
-
Article
Open AccessIncidence and risk of advanced age-related macular degeneration in eyes with drusenoid pigment epithelial detachment
To investigate the incidence and risk of advanced age-related macular degeneration (AMD), including geographic atrophy (GA) and macular neovascularization (MNV), in eyes with drusenoid pigment epithelial detac...
-
Article
Association of CRP levels with ARMS2 and CFH variants in age-related macular degeneration
To investigate whether plasma high sensitivity C-reactive protein (hs-CRP) level is associated with exudative age-related macular degeneration (AMD) as well as variants of ARMS2 A69S and CFH I62V in patients with...
-
Article
Open AccessGenetic factors associated with response to as-needed aflibercept therapy for typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
In the present study, we investigated the association between susceptible genetic variants to age-related macular degeneration (AMD) and response to as-needed intravitreal aflibercept injection (IAI) therapy f...
-
Article
Pseudodrusen pattern and development of late age-related macular degeneration in the fellow eye of the unilateral case
To investigate whether the development of late age-related macular degeneration (AMD) in fellow eyes with pseudodrusen is associated with the pseudodrusen pattern in patients with unilateral exudative AMD.
-
Article
Open AccessClinical and genetic characteristics of pachydrusen in patients with exudative age-related macular degeneration
We investigated the clinical and genetic characteristics of patients with unilateral exudative age-related macular degeneration (AMD), including typical AMD, polypoidal choroidal vasculopathy, and retinal angi...
-
Article
AREDS simplified severity scale as a predictive factor for response to aflibercept therapy for typical neovascular age-related macular degeneration
To investigate whether the severity of the condition in the untreated fellow eye is a predictive factor for the response to intravitreal aflibercept injection (IAI) for exudative age-related macular degenerati...
-
Article
Open AccessComparison of two-year outcomes after photodynamic therapy with ranibizumab or aflibercept for polypoidal choroidal vasculopathy
Photodynamic therapy (PDT) combined with intravitreal anti-vascular endothelial growth factor (VEGF) agents is currently the first-line treatment for polypoidal choroidal vasculopathy (PCV), along with anti-VE...
-
Article
Open AccessA prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration
We conducted a genome-wide association study (GWAS) on the outcome of anti-VEGF treatment for exudative age-related macular degeneration (AMD) in a prospective cohort. Four hundred and sixty-one treatment-naïv...
-
Article
Prevalence and characteristics of pseudodrusen subtypes in advanced age-related macular degeneration
The purpose of our study was to investigate the clinical and genetic characteristics of pseudodrusen subtypes and their incidence in advanced age-related macular degeneration (AMD).
-
Article
Open AccessIncidence and risk factors of retreatment after three-monthly aflibercept therapy for exudative age-related macular degeneration
Though anti-vascular endothelial growth factor therapy has become the standard treatment for exudative age-related macular degeneration (AMD), retreatment after the initial loading injection is inevitable in m...
-
Article
Comparison of initial treatment between 3-monthly intravitreal aflibercept monotherapy and combined photodynamic therapy with single intravitreal aflibercept for polypoidal choroidal vasculopathy
To compare the efficacy of two different initial treatment modalities on visual outcome, need for retreatment, and angiographic improvement during 12-month follow-up for polypoidal choroidal vasculopathy (PCV).
-
Article
Retreatment of polypoidal choroidal vasculopathy after photodynamic therapy combined with intravitreal ranibizumab
To investigate the incidence, risk factors and effect on visual improvement of retreatment within 60 months after initial photodynamic therapy (PDT) combined with intravitreal ranibizumab (IVR) in eyes with tr...
-
Article
Tissue-type plasminogen activator-assisted drainage of suprachoroidal hemorrhage showing a kissing configuration
