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  1. Article

    Open Access

    Whole-cycle management of women with epilepsy of child-bearing age: ontology construction and application

    The effective management of epilepsy in women of child-bearing age necessitates a concerted effort from multidisciplinary teams. Nevertheless, there exists an inadequacy in the seamless exchange of knowledge a...

    Yilin **a, Yifei Duan, Leihao Sha in BMC Medical Informatics and Decision Making (2024)

  2. Article

    Open Access

    Heterogeneity in susceptibility to polycystic ovary syndrome among women with epilepsy

    Epilepsy comorbidities adversely affect the quality of life of patients. Women with epilepsy are at a high risk of comorbid endocrine disorders. Among them, the polycystic ovary syndrome (PCOS) has a threefold...

    Leihao Sha, Yiming Wu, Wanlin Lai, Yifei Duan, Yilin **a, Lei Chen in Acta Epileptologica (2023)

  3. Article

    Open Access

    Two cases of anesthetics-induced epileptic seizures: a case report and literature review

    Anesthetics like propofol have been reported to be capable of controlling status epilepticus. However, we have observed during daily clinical work that some anesthetics can induce epileptic seizures. Therefore...

    Wanling Li, Wanlin Lai, Anjiao Peng, Lei Chen in Acta Epileptologica (2022)

  4. No Access

    Article

    Metabolomics Provides Novel Insights into Epilepsy Diagnosis and Treatment: A Review

    Epilepsy is one of the most common diseases of the central nervous system. The diagnosis of epilepsy mainly depends on electroencephalograms and symptomatology, while diagnostic biofluid markers are still lack...

    Wanlin Lai, Dan Du, Lei Chen in Neurochemical Research (2022)

  5. Article

    Open Access

    Managing reproductive problems in women with epilepsy of childbearing age

    Girls and women constitute nearly 50% of all epilepsy cases. Apart from the disease symptoms, epilepsy and antiseizure medications (ASMs) may also affect the reproductive function, pregnancy and even the healt...

    Wanlin Lai, Shixu He, Dong Zhou, Lei Chen in Acta Epileptologica (2021)

  6. No Access

    Article

    Integrative analysis of non-targeted lipidomic data and brain structural imaging identifies phosphatidylethanolamine associated with epileptogenesis

    Epilepsy is a chronic disease, while epileptogenesis is a latent period where brain will be transformed into an epileptic one. Mechanisms of epileptogenesis remain unclear.

    **angmiao Qiu, Lu Zhang, Masako Kinoshita, Wanlin Lai, Wen Zheng in Metabolomics (2020)