-
Article
Anti-conflict effects of benzodiazepines in rhesus monkeys: relationship with therapeutic doses in humans and role of GABAA receptors
Conflict procedures are used to study mechanisms underlying the anxiolytic effects of benzodiazepines (BZs). We established a conflict procedure with rhesus monkeys in order to examine the role of GABAA receptors...
-
Article
Repeated limited access to IV cocaine self-administration: conditioned autonomic rhythmicity illustrating ”predictive homeostasis”
Rationale: Regular cocaine self-administration may act as a ”Zeitgeber” in animals and humans, and physiological rhythms may peak at the time when the drug is usually self-administered.
-
Chapter
Alcohol, GABAA-Benzodiazepine Receptor Complex, and Aggression
Neurobiological investigations have become productive since experimental protocols were developed that engender large increases in aggressive behavior after acute alcohol challenges in individual experimental ...
-
Article
Alcohol, anxiolytics and social stress in rats
The main objective was to compare the anxiolytic-like profiles of alcohol, diazepam and gepirone along the stress intensity gradient which characterizes consecutive phases of a social confrontation. The acute ...
-
Article
Behavioral and autonomic responses to intermittent social stress: differential protection by clonidine and metoprolol
The present study investigated physiological and pharmacological characteristics of socially “stressed” animals. Specifically, we examined (1) to what degree autonomic and behavioral “stress” reactions during ...
-
Article
Prevention of the pro-aggressive effects of alcohol in rats and squirrel monkeys by benzodiazepine receptor antagonists
Pharmacological manipulations at the benzodiazepine-GABAA-chloride ionophore receptor complex modify some of the behavioral and physiological actions of alcohol (ethanol). The interactions between alcohol, benzod...
-
Article
“Anxiolytic” and “anxiogenic” benzodiazepines and β-carbolines: effects on aggressive and social behavior in rats and squirrel monkeys
Ethopharmacological studies on the behavior of socially housed rats and squirrel monkeys were conducted to explore the role of the benzodiazepine GABAA-coupled ionophore receptor complex in aggressive and social ...
-
Article
Alcohol and “bursts” of aggressive behavior: ethological analysis of individual differences in rats
A quantitative ethological analysis of rodent aggression was performed in order to characterize the aggression-heightening effects of alcohol in certain individuals. In dyadic confrontations, a resident rat pu...
-
Chapter
Ethology and Neuropharmacology: Rodent Ultrasounds
One of the most fascinating and instructive illustrations of how neural networks mediate complex communication comes from the neuroethological studies with zebra finches and canaries that sing to court mates a...
-
Chapter
Short and Long Term Physiological and Neurochemical Adaptations to Social Conflict
Social conflict engenders behavioral and physiological phonemena that are relevant to the concept of stress. Attack and threat by an opponent leads to profound behavioral, physiological and neurochemical react...
