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    Reference Work Entry In depth

    The Promise and Challenge of Microbial Alginate Production: A Product with Novel Applications

    Alginate is a polysaccharide that has various established applications in food, textile, and pharmaceutical industries for its viscosifying and gelling properties. In the last two decades, and owing to their b...

    Wael Sabra in Polysaccharides of Microbial Origin (2022)

  2. No Access

    Living Reference Work Entry In depth

    The Promise and Challenge of Microbial Alginate Production: A Product with Novel Applications

    Alginate is a polysaccharide that has various established applications in food, textile, and pharmaceutical industries for its viscosifying and gelling properties. In the last two decades, and owing to their b...

    Wael Sabra in Polysaccharides of Microbial Origin

  3. Article

    Open Access

    Co-cultures with integrated in situ product removal for lactate-based propionic acid production

    Propionic acid (PA) is a valuable organic acid for the food and feed industry, but no bioproduction at industrial scale exists so far. As product inhibition is a major burden for bioprocesses producing organic...

    Ludwig Selder, Wael Sabra, Nikolai Jürgensen in Bioprocess and Biosystems Engineering (2020)

  4. Article

    Open Access

    Substrates and oxygen dependent citric acid production by Yarrowia lipolytica: insights through transcriptome and fluxome analyses

    Unlike the well-studied backer yeast where catabolite repression represents a burden for mixed substrate fermentation, Yarrowia lipolytica, an oleaginous yeast, is recognized for its potential to produce single c...

    Wael Sabra, Rajesh Reddy Bommareddy, Garima Maheshwari in Microbial Cell Factories (2017)

  5. Article

    Open Access

    Metabolic and proteomic analyses of product selectivity and redox regulation in Clostridium pasteurianum grown on glycerol under varied iron availability

    Clostridium pasteurianum as an emerging new microbial cell factory can produce both n-butanol (BuOH) and 1,3-propanediol (1,3-PDO), and the pattern of product formation changes signifi...

    Christin Groeger, Wei Wang, Wael Sabra, Tyll Utesch in Microbial Cell Factories (2017)

  6. Article

    Open Access

    Fermentation of mixed substrates by Clostridium pasteurianum and its physiological, metabolic and proteomic characterizations

    Clostridium pasteurianum is becoming increasingly attractive for the production of chemicals and fuels such as n-butanol and 1,3-propanediol. Previously we have shown that dual substra...

    Wael Sabra, Wei Wang, Sruthi Surandram, Christin Groeger in Microbial Cell Factories (2016)

  7. Article

    Open Access

    Metabolic network analysis and experimental study of lipid production in Rhodosporidium toruloides grown on single and mixed substrates

    Microbial lipids (triacylglycerols, TAG) have received large attention for a sustainable production of oleochemicals and biofuels. Rhodosporidium toruloides can accumulate lipids up to 70% of its cell mass under ...

    Rajesh Reddy Bommareddy, Wael Sabra, Garima Maheshwari in Microbial Cell Factories (2015)

  8. No Access

    Article

    Microbial community composition and dynamics in high-temperature biogas reactors using industrial bioethanol waste as substrate

    Stillage, which is generated during bioethanol production, constitutes a promising substrate for biogas production within the scope of an integrated biorefinery concept. In this study, a microbial community wa...

    Immo Röske, Wael Sabra, Heiko Nacke, Rolf Daniel in Applied Microbiology and Biotechnology (2014)

  9. Article

    Open Access

    Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation

    The kinetics of growth, acid and solvent production in batch culture of Clostridium pasteurianum DSMZ 525 were examined in mixed or mono-substrate fermentations. In pH-uncontrolled batch cultures, the addition of...

    Wael Sabra, C. Groeger, P. N. Sharma in Applied Microbiology and Biotechnology (2014)

  10. Article

    Open Access

    Co-cultivation of Lactobacillus zeae and Veillonella criceti for the production of propionic acid

    In this work a defined co-culture of the lactic acid bacterium Lactobacillus zeae and the propionate producer Veillonella criceti has been studied in continuous stirred tank reactor (CSTR) and in a dialysis membr...

    David Dietz, Wael Sabra, An-** Zeng in AMB Express (2013)

  11. No Access

    Chapter

    Microbial Production of Alginates: Physiology and Process Aspects

    Presently, most of the alginate produced commercially is still obtained from algae, although it is subjected to variations in quality and quantity due to changes of climate and sources. Alginate can also be bi...

    Wael Sabra, An ** Zeng in Alginates: Biology and Applications (2009)

  12. No Access

    Chapter

    The Use of a C-FOS-GFP Reporter System for Monitoring Apoptosis of Animal Cells Induced by Exotoxins of Pseudomonas Aeruginosa

    A reporter gene system based on the expression of green fluorecense protein (GFP) was developed for monitoring the dynamics of apoptotic cell death. The expression plasmid was stably introduced into CHO-DHFR cel...

    Dr **g-**u Bi, Dr Manfred Wirth in Animal Cell Technology: From Target to Mar… (2001)