-
Article
Comparison of direct and indirect alcohol markers with PEth in blood and urine in alcohol dependent inpatients during detoxication
The importance of direct and indirect alcohol markers to evaluate alcohol consumption in clinical and forensic settings is increasingly recognized. While some markers are used to prove abstinence from ethanol,...
-
Article
Alkoholkonsummarker
Alkoholkonsummarker sind im Körper gebildete Stoffe, die eine stattgehabte Alkoholaufnahme anzeigen. Diese Biomarker der Äthanolaufnahme sind bei unverändert hohem Alkoholkonsum in der Bevölkerung für klinisch...
-
Article
Identification of 48 homologues of phosphatidylethanol in blood by LC-ESI-MS/MS
Phosphatidylethanol (PEth) is an abnormal phospholipid carrying two fatty acid chains. It is only formed in the presence of ethanol via the action of phospholipase D (PLD). Its use as a biomarker for alcohol c...
-
Article
Detection and identification of 700 drugs by multi-target screening with a 3200 Q TRAP® LC-MS/MS system and library searching
The multi-target screening method described in this work allows the simultaneous detection and identification of 700 drugs and metabolites in biological fluids using a hybrid triple-quadrupole linear ion trap ...
-
Article
Suicidal poisoning with mercaptodimethur–morphological findings and toxicological analysis
In the western countries, the number of fatal intoxications with plant protecting agents has decreased to some extent due to laws restricting the use of highly toxic pesticides like halogenated hydrocarbons. N...
-
Article
Intoxikation mit γ-Hydroxybutyrat
Mittlerweile hat die Droge γ-Hydroxybutyrat (GHB), auch als „liquid ecstasy“ bekannt, Europa erreicht. γ-Hydroxybutyrat ist, insbesondere in flüssiger Form, schwer dosierbar, so dass es in Unkenntnis der genau...
-
Article
Post-mortem detection and identification of sildenafil (Viagra) and its metabolites by LC/MS and LC/MS/MS
The highly putrefied corpse of an 80-year-old man was found in the apartment which he had rented to a prostitute. A package of Viagra 25 was found beside the corpse and three tablets were missing. Autopsy rev...
-
Article
Automated solid-phase extraction and two-step derivatisation for simultaneous analysis of basic illicit drugs in serum by GC/MS
A combination of automated solid-phase extraction (SPE) and subsequent two-step derivatisation has been developed for the simultaneous analysis of basic drugs of abuse and cocaine metabolites in serum samples...
-
Article
Abstracts
-
Article
Bestimmungsgrenzen für den Nachweis von Cannabinoiden in Serum
The limits of quantitation for cannabinoids in serum using automated solid-phase extraction (SPE) and gas chromatography-mass spectrometry (GC/MS) have been determined. Extraction was performed automatically u...
-
Article
Farbmetrische Untersuchungen der menschlichen Kopfhaare
An essential parameter for the incorporation of drugs and narcotics into head hair is the content of hair pigment (melanins). Toxicological studies of hair should therefore take the colour of the hair into co...
-
Article
013 Characterization of primary structure and microheterogeneity of fatty acid acylated lipoproteins by 252Cf-plasma desorption and electrospray mass spectrometry
-
Article
Verbesserte Methode zum serienmäßigen quantitativen Nachweis von Insecticidrückständen bei Obst und Gemüse
Die technischen Abänderungen, die unsere Methode in den letzten 4 Jahren bei uns erfuhr, sowie die Ergebnisse systematischer Untersuchungen zur Steigerung der Leistungsfähigkeit bzw. Vereinfachung des Analysen...
-
Article
Saatgutinkrustierung mit Insektiziden, eine der bedenklichsten Pflanzenschutzmaßnahmen
-
Article
Quantitativer biologischer Nachweis von Insektizidrückständen in Pflanzenmaterial mit höheren Gehalten an Lauch- und Senfölen
-
Article
Zur Bestimmung der gesamten schwefligen Säure in Süßmosten
Von den bisherigen Methoden zur Bestimmung der gesamten schwefligen Säure in Süßmosten erweist sich die Arbeitsweise: Destillation mit nachfolgender maßanalytischer Bestimmung der schwefligen Säure, am vorteil...
