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  1. No Access

    Article

    Hypoxia increases Sca-1/CD44 co-expression in murine mesenchymal stem cells and enhances their adipogenic differentiation potential

    Mesenchymal stem cells (MSCs) are usually cultured under normoxic conditions (21% oxygen). However, in vivo, the physiological “niches” for MSCs have a much lower oxygen tension. Because of their plasticity, s...

    M. G. Valorani, A. Germani, W. R. Otto, L. Harper, A. Biddle… in Cell and Tissue Research (2010)

  2. No Access

    Article

    Trefoil factors

    Trefoil factor family (TFF) peptides have many in vivo and in vitro effects on restitution, wound healing, apoptosis, cell motility, adhesion and vectorial ion pum**, amongst others. 125I-TFF peptides bind to c...

    W. R. Otto, L. Thim in Cellular and Molecular Life Sciences CMLS (2005)

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    Article

    Influence of human skin injury on regeneration of sensory neurons

    The regeneration of sensory nerve fibres is regulated by trophic factors released from their target tissue, particularly the basal epidermis, and matrix molecules. Means to modulate this response may be useful...

    O. Taherzadeh, W. R. Otto, U. Anand, J. Nanchahal, P. Anand in Cell and Tissue Research (2003)

  4. No Access

    Article

    Trefoil factor family (TFF)-domain peptides in the mouse: embryonic gastrointestinal expression and wounding response

     Trefoil factor family (TFF)-domain peptides are mucin-associated molecules that play a role in maintaining gastrointestinal (GI) epithelial integrity. They are expressed in specific patterns in adult mammals,...

    W. R. Otto, Ketan Patel in Anatomy and Embryology (1999)

  5. Article

    Energy expenditure in children

    B. G. MILLER, W. R. OTTO in Nature (1976)

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