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Article
The Electric Field Gradient in Noncubic Metals and Alloys
The electric field gradient (efg) present in noncubic solids causes an energy-splitting of the nuclear levels via the quadrupole hyperfine interaction. During the last few years the perturbed angular correlati...
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Article
Investigation of Lattice Defects in HCP Metals
With the perturbed angular correlation and distribution methods we studied the trap** and annealing of lattice defects in the hcp metals Cd and Zn. The defects were produced (i) by proton irradiation, (ii) b...
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Article
Interactions of melatonin with the liver microsomal cytochrome P450 system of rats and humans in vitro and effects on the P450 system and the antioxidative status in rat liver after acute treatment
In vitro melatonin binds to human and rat liver microsomal cytochrome P-450 (P450) according to a type II substrate. The affinity is similar to that of aniline with a general left-shift. Melatonin interferes w...
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Article
Interaction of chlormezanone enantiomers with rat liver microsomes
Both chlormezanone enantiomers, for the first time obtained by enantiospecific HPLC with a 100% yield, bind to oxidized cytochrome P-450 in rat liver microsomes with a binding curve according to type I, simila...
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Article
Interaction of chlormezanone with rat liver microsomes and its degradation
Chlormezanone binds to oxidized cytochrome P450 in rat liver microsomes with a binding curve according to type I like hexobarbital but less pronounced and with a general shift to the left. Ethylmorphine N-deme...
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Chapter and Conference Paper
The Glutathione System in Rat Liver Chronically Injured by Thioacetamide
Glutathione (reduced form: GSH, oxidized form: GSSG) serves a broad spectrum of functions in the liver (for review see Meister and Anderson 1983; Kretzschmar and Klinger 1990). GSH is transported into the circ...
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Chapter and Conference Paper
Influence of Glucocorticoids on the Postnatal Development of Cytochrome P-450 in Rat Liver
It is known that the activity of the cytochrome P-450 (P-450) monooxygenase system, which is responsible for detoxication as well as toxiciation of many xenobiotics, depends on age (Klinger 1982). Among other ...
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Chapter and Conference Paper
Monooxygenase Activity of Fish Liver in Biomonitoring Aquatic Environment
The hepatic biotransformation activity of four cultivated freshwater fish, Amur carp (Ctenopharyngodon idella), carp (Cyprinus carpio), rainbow trout (Salmo gairdneri) and tench (Tinca tinca) were studied one day...
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Chapter and Conference Paper
Influence of Age, Hexobarbital, and Aniline on NADPH/NADH Dependent Hydrogen Peroxide Production in Rat Hepatic Microsomes
Hepatic microsomal H2O2 production (oxidase function of microsomal cytochrome P-450) is strongly dependent on NADPH or NADH concentration. NADH increases H2O2 production after the addition of a supraoptimal conce...
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Chapter and Conference Paper
Increased Response of Cytochrome P-450 Dependent Biotransformation Reactions in Rat Liver to Repeated Administration of Inducers
A single intraperitoneal administration of 3-methylcholanthrene (3 MC) or β-naphthoflavone (BNF) increased aryl hydrocarbon hydroxylase (AHH) and 7-ethoxyresorufin 0-deethylase (EROD) activities. Following a seco...
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Chapter and Conference Paper
Separation of Immature and Adult Rat Hepatocytes into Distinct Subpopulations by Centrifugal Elutriation
Several subpopulations of hepatocytes with increasing cell diameters were isolated, the smaller cells were attributed to the periportal area, the larger ones to the perivenous region. Profiles of total cytochr...
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Article
Hyperfine interactions of highly diluted Eu in Sm
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Article
Correlated radiation damage in cadmium
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Article
The effect of temperature and concentration on the electric field gradient in binary indium alloys
The concentration and temperature dependence of the quadrupole hyperfine interaction of111Cd in InTl (hcp),InPb (fct),InTl (fct) andInCd (fct and fcc) alloys were studied using the perturbed angular correlation t...
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Article
The electric field gradient in non-transition
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Article
The electric field gradient in Cd−Mg alloys
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Article
Magnetic and electric hyperfine interactions in the system EuSm
Magnetic and electric hyperfine interactions in the system EuSm were investigated with the isomeric 11/2− state in145Eu by applying the time-differential perturbed angular distribution (TDPAD) method. The tempera...
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Chapter
Quadrupole Interaction in Noncubic Metals and Alloys
During the last few years the perturbed angular correlation method /1/ has proved to be a powerful experimental tool for investigating the electric field gradient (efg) in metals via the nuclear quadrupole int...
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Chapter
Investigation of Lattice Defects in HCP Metals
Because of the microscopic nature of lattice defects, nuclear methods are well suited for their investigation. In these methods an atomic nucleus serves as a probe which monitors its surroundings via the hyper...
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Chapter and Conference Paper
Hepatic Nuclear Free and Engaged RNA-Polymerases in Young Rats Pretreated with 3-Methylcholanthrene
In 3-methylcholanthrene (3-MC)-pretreated young rats the free and engaged RNA polymerases were investigated in detail both in the nucleolar and nucleoplasmic fractions. Both functional forms of the nucleolar R...
