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Chapter
Haemodynamic Manifestations Of Blood-dialyser Interactions And Their Modification In An Animal Model
Blood-foreign surface interactions occurring in extracorporeal devices such as the artificial kidney may lead to clinically significant problems. One such problem that has been well recognised is the periphera...
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Article
The case for steroids: another viewpoint
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Article
Heart injury in head-injured adolescents
Of 19 adolescents (ages 10–18) admitted consecutively because of major blunt-impact trauma, 15 had head injuries (Glasgow coma scales 4–15). Eight had cardiac injury (42%), as demonstrated by cardiac wall-moti...
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Chapter
Right Ventricular Performance in the Adult Respiratory Distress Syndrome
The Adult Respiratory Distress Syndrome (ARDS) is a catastrophic form of acute hypoxemic respiratory failure which usually follows a variety of direct and indirect insults to the lung’s gas-exchanging membrane...
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Chapter
Circulatory Abnormalities in the Sepsis Syndrome
With a mortality rate of 50% – 80%, sepsis is a major cause of death in critically ill patients. Currently, it is appreciated that death resulting from sepsis is not as clearly related to perturbations of cent...
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Chapter and Conference Paper
The Role of Tissue Hypoxia in Multiple Organ Failure
The metabolic theory of circulatory control proposes that the regulated vari able is tissue oxygen (O2) flux [1, 2] and that the primary function of the circulation is to, thereby, continuously couple blood flow ...
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Chapter
Kreislaufveränderungen beim septischen Syndrom
Mit einer Mortalitätsrate von 50–80% ist die Sepsis eine häufige Todesursache schwerstkranker Patienten. Derzeit wird nicht mehr so eindeutig wie früher eine Störung der zentralen Kreislaufregulation bzw. ein ...
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Chapter and Conference Paper
Multiple Systems Organ Failure
The most common preterminal diagnosis in Critical Care Medicine is MULTIPLE SYSTEMS ORGAN FAILURE (MSOF). This term has been used to describe a process which is characterized by the sequential dysfunction and ...
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Chapter
Myocardial Oxygen Metabolism in the Sepsis Syndrome
Multiple Systems Organ Failure (MOF) describes a syndrome which is characterized by the sequential dysfunction and ultimately failure of vital organs in critically ill patients. Although many factors have been...
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Chapter
Models of Sepsis: Subacute Peritonitis in Sheep and Rats
To avoid incorrect conclusions research should be designed and conducted with careful attention to datails and underlying assumptions. The study of sepsis and multiple organ failure challenges the investigator...
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Chapter and Conference Paper
Issues in Colloid and Transfusion Therapy of Sepsis
Sepsis is a systemic illness characterized by an uncontrolled host inflammatory response, usually to severe bacterial infection [1]. Morbidity in sepsis relates to the development of multiple organ dysfunction...
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Chapter
Fluid Therapy in Sepsis
Sepsis is a systemic illness characterized by an uncontrolled host inflammatory response, usually to severe infection [1]. Patients with sepsis are frequently admitted to the ICU for life-support of multiple o...
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Chapter
Cardiocirculation in Sepsis
Sepsis is a syndrome in which organ dysfunction frequently determines outcome. Myocardial dysfunction is not only part of the process of organ dysfunction, but may contribute to its further propagation. For ex...
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Chapter and Conference Paper
Continuous Quality Improvement
Increasingly, the quality of health care has come under intense scrutiny in the hospital sector. Although there is no unanimity on the most appropriate definition of quality when applied to health care, the McMas...
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Chapter
Role of RBC Transfusion Therapy in Sepsis
Sepsis is a clinical syndrome that arises because of an inappropriate and excessive host inflammatory response. Recent work has demonstrated that this syndrome is also characterized by the development of quant...
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Article
Round table conference on clinical trials for the treatment of sepsis Brussels, March 12–14, 1994
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Article
Sepsis, SIRS and infection
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Chapter and Conference Paper
Sepsis, Anemia, and Tissue O2 Availability
Complicating severe bacterial infection, sepsis is a clinical syndrome distinguished by systemic inflammation and widespread tissue injury. As survival has been associated with improving tissue O2 availability [1...
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Article
Free Papers
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Chapter and Conference Paper
O2 Transport in the Peripheral Circulation in Sepsis
Complicating severe bacterial infection, sepsis is a clinical syndrome distinguished by systemic microvascular inflammation and widespread tissue injury. The incidence of sepsis is increasing as society ages a...