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  1. No Access

    Chapter

    Haemodynamic Manifestations Of Blood-dialyser Interactions And Their Modification In An Animal Model

    Blood-foreign surface interactions occurring in extracorporeal devices such as the artificial kidney may lead to clinically significant problems. One such problem that has been well recognised is the periphera...

    R. M. Lindsay, J. F. Walker, W. J. Sibbald in Biomaterials in Artificial Organs (1984)

  2. No Access

    Article

    The case for steroids: another viewpoint

    W. J. Sibbald in Intensive Care Medicine (1984)

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    Article

    Heart injury in head-injured adolescents

    Of 19 adolescents (ages 10–18) admitted consecutively because of major blunt-impact trauma, 15 had head injuries (Glasgow coma scales 4–15). Eight had cardiac injury (42%), as demonstrated by cardiac wall-moti...

    G. R. Sutherland, A. L. Amacher, W. J. Sibbald, A. L. Driedger in Child's Nervous System (1985)

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    Chapter

    Right Ventricular Performance in the Adult Respiratory Distress Syndrome

    The Adult Respiratory Distress Syndrome (ARDS) is a catastrophic form of acute hypoxemic respiratory failure which usually follows a variety of direct and indirect insults to the lung’s gas-exchanging membrane...

    L. D. Oliphant, W. J. Sibbald in Cardiopulmonary Interactions in Acute Respiratory Failure (1987)

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    Chapter

    Circulatory Abnormalities in the Sepsis Syndrome

    With a mortality rate of 50% – 80%, sepsis is a major cause of death in critically ill patients. Currently, it is appreciated that death resulting from sepsis is not as clearly related to perturbations of cent...

    W. J. Sibbald, R. F. Raper, A. D. Bersten in Sepsis (1989)

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    Chapter and Conference Paper

    The Role of Tissue Hypoxia in Multiple Organ Failure

    The metabolic theory of circulatory control proposes that the regulated vari able is tissue oxygen (O2) flux [1, 2] and that the primary function of the circulation is to, thereby, continuously couple blood flow ...

    W. J. Sibbald, A. Bersten, F. S. Rutledge in Clinical Aspects of O2 Transport and Tissu… (1989)

  7. No Access

    Chapter

    Kreislaufveränderungen beim septischen Syndrom

    Mit einer Mortalitätsrate von 50–80% ist die Sepsis eine häufige Todesursache schwerstkranker Patienten. Derzeit wird nicht mehr so eindeutig wie früher eine Störung der zentralen Kreislaufregulation bzw. ein ...

    W. J. Sibbald, R. F. Raper, A. D. Bersten in Sepsis (1989)

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    Chapter and Conference Paper

    Multiple Systems Organ Failure

    The most common preterminal diagnosis in Critical Care Medicine is MULTIPLE SYSTEMS ORGAN FAILURE (MSOF). This term has been used to describe a process which is characterized by the sequential dysfunction and ...

    F. S. Rutledge, W. J. Sibbald in Oxygen Transport in the Critically Ill Patient (1990)

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    Chapter

    Myocardial Oxygen Metabolism in the Sepsis Syndrome

    Multiple Systems Organ Failure (MOF) describes a syndrome which is characterized by the sequential dysfunction and ultimately failure of vital organs in critically ill patients. Although many factors have been...

    W. J. Sibbald in Tissue Oxygen Utilization (1991)

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    Chapter

    Models of Sepsis: Subacute Peritonitis in Sheep and Rats

    To avoid incorrect conclusions research should be designed and conducted with careful attention to datails and underlying assumptions. The study of sepsis and multiple organ failure challenges the investigator...

    C. M. Martin, A. Neal, W. J. Sibbald in Pathophysiology of Shock, Sepsis, and Organ Failure (1993)

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    Chapter and Conference Paper

    Issues in Colloid and Transfusion Therapy of Sepsis

    Sepsis is a systemic illness characterized by an uncontrolled host inflammatory response, usually to severe bacterial infection [1]. Morbidity in sepsis relates to the development of multiple organ dysfunction...

    H. Morisaki, W. J. Sibbald in Yearbook of Intensive Care and Emergency Medicine 1993 (1993)

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    Chapter

    Fluid Therapy in Sepsis

    Sepsis is a systemic illness characterized by an uncontrolled host inflammatory response, usually to severe infection [1]. Patients with sepsis are frequently admitted to the ICU for life-support of multiple o...

    W. J. Sibbald in Sepsis (1994)

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    Chapter

    Cardiocirculation in Sepsis

    Sepsis is a syndrome in which organ dysfunction frequently determines outcome. Myocardial dysfunction is not only part of the process of organ dysfunction, but may contribute to its further propagation. For ex...

    F. Bloos, W. J. Sibbald in Sepsis (1994)

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    Chapter and Conference Paper

    Continuous Quality Improvement

    Increasingly, the quality of health care has come under intense scrutiny in the hospital sector. Although there is no unanimity on the most appropriate definition of quality when applied to health care, the McMas...

    W. J. Sibbald in Yearbook of Intensive Care and Emergency Medicine (1995)

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    Chapter

    Role of RBC Transfusion Therapy in Sepsis

    Sepsis is a clinical syndrome that arises because of an inappropriate and excessive host inflammatory response. Recent work has demonstrated that this syndrome is also characterized by the development of quant...

    W. J. Sibbald, G. S. Doig, H. Morisaki in Clinical Trials for the Treatment of Sepsis (1995)

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    Article

    Round table conference on clinical trials for the treatment of sepsis Brussels, March 12–14, 1994

    W. J. Sibbald, J. -L. Vincent, Mrs Suzanne Smitz-de Smet in Intensive Care Medicine (1995)

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    Article

    Sepsis, SIRS and infection

    W. J. Sibbald, G. Doig, K. J. Inman in Intensive Care Medicine (1995)

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    Chapter and Conference Paper

    Sepsis, Anemia, and Tissue O2 Availability

    Complicating severe bacterial infection, sepsis is a clinical syndrome distinguished by systemic inflammation and widespread tissue injury. As survival has been associated with improving tissue O2 availability [1...

    W. J. Sibbald, F. Bloos, H. Morisaki in Yearbook of Intensive Care and Emergency Medicine (1996)

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    Article

    Free Papers

    A. Sielenkämper, C. M. Martin, S. Madorin, I. Chin-Yee in Intensive Care Medicine (1996)

  20. No Access

    Chapter and Conference Paper

    O2 Transport in the Peripheral Circulation in Sepsis

    Complicating severe bacterial infection, sepsis is a clinical syndrome distinguished by systemic microvascular inflammation and widespread tissue injury. The incidence of sepsis is increasing as society ages a...

    O. Eichelbroenner, F. M. Bloos in Yearbook of Intensive Care and Emergency M… (1997)

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