36 Result(s)

Chapter and Conference Paper

Managing and Leading in Critical Care

W. J. Sibbald in Intensive Care Medicine in 10 Years (2006)

Chapter and Conference Paper

Re-organizing Health Care Systems to Optimize Critical Care Outcomes

Short-term health outcomes maybe an attractive measure of success for individual hospital departments. For example a coronary care unit (CCU) may feel that improvements in morbidity and mortality following car...

M. Hartleib, W.J. Sibbald in Surviving Intensive Care (2003)

Chapter and Conference Paper

Identifying the Patient-at-Risk: Technology and ICU Outreach Services

The provision of intensive care to critically-ill patients is a very costly endeavor. Intensive care units (ICUs) account for approximately 10% of inpatient acute care beds in the United States [1, 2], and thi...

D. C. Scales, J. Granton, W. J. Sibbald in Intensive Care Medicine (2003)

Chapter

Introduction — Critical Care: Problems, Boundaries and Outcomes

As we enter a new millennium and complete almost half a century since the first intensive care units were developed, the conjunction is an opportune occasion on which to reflect on past achievements and future...

J. F. Bion, W. J. Sibbald in Evaluating Critical Care (2002)

Chapter

The Immunological Effects of Hypertonic Saline

Sporadic reports on the use of high salt crystalloid solutions, or hypertonic saline, date back to the beginning of the 20^th century. Hypertonic solutions were most often used to correct electrolyte abnormalities...

S. B. Rizoli, O. D. Rotstein, W. J. Sibbald in Intensive Care Medicine (2002)

Chapter and Conference Paper

The Immunological Effects of Hypertonic Saline

Sporadic reports on the use of high salt crystalloid solutions, or hypertonic saline, date back to the beginning of the 20^th century. Hypertonic solutions were most often used to correct electrolyte abnormalities...

S. B. Rizoli, O. D. Rotstein, W. J. Sibbald in Yearbook of Intensive Care and Emergency M… (2002)

Chapter

Translating the Evidence: Creating and Sustaining Change

The ability to change clinical practice patterns is a major determinant of clinical effectiveness in intensive care medicine, a discipline with a rapidly evolving knowledge base. A broad range of strategies ca...

W. J. Sibbald, G. K. Webster in Evaluating Critical Care (2002)

Chapter and Conference Paper

Pancreatic Dysfunction in Critical Illness

In recent years, multiple organ dysfunction syndrome (MODS) has been studied extensively because of its relationship to adverse outcome in sepsis. In fact, the dysfunction of organs such as the lung, the kidne...

B. Tribl, W. J. Sibbald in Yearbook of Intensive Care and Emergency Medicine 2001 (2001)

Article

Roundtable Conference on Tissue Oxygenation in Acute Medicine, Brussels, Belgium, 14–16 March 1998

W. J. Sibbald, K. Messmer, M. P. Fink in Intensive Care Medicine (2000)

Chapter and Conference Paper

Intestinal Microcirculation: Changes in Sepsis and Effect of Vasoactive Manipulation

Multiple organ dysfunction syndrome (MODS) continues to be a source of excessive morbidity and mortality in the critically ill population [1]. While the pathogenesis of MODS remains to be fully elucidated, a p...

L. C. H. Tham, C. M. Martin, W. J. Sibbald in Yearbook of Intensive Care and Emergency M… (2000)

Chapter and Conference Paper

The Red Blood Cell and Nitric Oxide

Primary intracellular targets for the biological actions of nitric oxide (NO) are iron and heme-containing proteins [1]. Quantitatively, the major reaction of NO in vivo is with oxyhemoglobin [2]. Therefore, whil...

J. Graf, O. Eichelbroenner, W. J. Sibbald in Yearbook of Intensive Care and Emergency M… (1999)

Chapter and Conference Paper

Development of Myocardial Tolerance to Ischemia/Reperfusion and Septic Injury

Myocardial resistance to ischemia/reperfusion (I/R) injury can be induced by pre-treating the myocardium with brief I/R episodes [1]. This protective effect of I/R pre-treatment is termed “pre-conditioning”. P...

R. R. Nevière, W. J. Sibbald in Yearbook of Intensive Care and Emergency Medicine 1998 (1998)

Chapter and Conference Paper

The Red Blood Cell: New Ideas About an Old Friend

With the introduction of the microscope in the early 1600s, scientists observed “red particles” in circulating fluid. Borel (1620–1689) and Kircher (1602–1680), both pioneer microscopists, descibed these objec...

O. Eichelbroenner, C. G. Ellis… in Yearbook of Intensive Care and Emergency M… (1998)

Article

Understanding the ICU business in Europe

W. J. Sibbald, L. M. Chen, C. M. Martin in Intensive Care Medicine (1997)

Chapter and Conference Paper

O₂ Transport in the Peripheral Circulation in Sepsis

Complicating severe bacterial infection, sepsis is a clinical syndrome distinguished by systemic microvascular inflammation and widespread tissue injury. The incidence of sepsis is increasing as society ages a...

O. Eichelbroenner, F. M. Bloos… in Yearbook of Intensive Care and Emergency M… (1997)

Article

Free Papers

A. Sielenkämper, C. M. Martin, S. Madorin, I. Chin-Yee… in Intensive Care Medicine (1996)

Chapter and Conference Paper

Sepsis, Anemia, and Tissue O₂ Availability

Complicating severe bacterial infection, sepsis is a clinical syndrome distinguished by systemic inflammation and widespread tissue injury. As survival has been associated with improving tissue O₂ availability [1...

W. J. Sibbald, F. Bloos, H. Morisaki in Yearbook of Intensive Care and Emergency Medicine (1996)

Article

Sepsis, SIRS and infection

W. J. Sibbald, G. Doig, K. J. Inman in Intensive Care Medicine (1995)