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Open AccessEvaluation and treatment of gastrointestinal bleeding in patients taking anticoagulants presenting to the emergency department
This manuscript is a consensus document of an expert panel on the Evaluation and Treatment of Gastrointestinal Bleeding in Patients Taking Anticoagulants Presenting to the Emergency Department, sponsored by th...
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Open AccessThe Increased Clinical and Economic Burden of Hyperkalemia in Medicare Patients Admitted to Long-Term Care Settings
Older patients are at increased risk for hyperkalemia (HK). This study describes the prevalence, recurrence, and clinical and economic burden of HK in Medicare patients admitted to a long-term care (LTC) setting.
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Open AccessOpioid-Induced Constipation: Cost Impact of Approved Medications in the Emergency Department
Opioid-induced constipation (OIC) prescription medications (OIC-Rx) like methylnaltrexone subcutaneous (SC) have shown efficacy in treating OIC in the emergency department (ED). This study aimed to describe an...
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Correction: The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure
Adverse posttraumatic neuropsychiatric sequelae (APNS) are common among civilian trauma survivors and military veterans. These APNS, as traditionally classified, include posttraumatic stress, postconcussion sy...
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Morphine Use in the Treatment of Acute Cardiogenic Pulmonary Edema and Its Effects on Patient Outcome: A Systematic Review
To analyze whether the use of morphine, as initial treatment in acute cardiogenic pulmonary edema (ACPE), has an impact in clinical outcomes and mortality. A systematic review of the literature was performed, ...
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The value of sPESI for risk stratification in patients with pulmonary embolism
Various risk stratification methods exist for patients with pulmonary embolism (PE). We used the simplified Pulmonary Embolism Severity Index (sPESI) as a risk-stratification method to understand the Veterans ...
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The role of atrial fibrillation in the short-term outcomes of patients with acute heart failure
To investigate whether the presence of atrial fibrillation (AF) is independently associated with adverse short-term outcomes in patients diagnosed with acute heart failure (AHF) in the emergency department (ED).
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Open AccessManagement of hyperkalemia in the acutely ill patient
To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients.
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Short-term outcomes of heart failure patients with reduced and preserved ejection fraction after acute decompensation according to the final destination after emergency department care
To compare short-term outcomes after an episode of acute heart failure (AHF) in patients with reduced and preserved ejection fractions (HFrEF, < 40%; and HFpEF, > 49%; respectively) according to their destinat...
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Open AccessBiomarkers of Acute Stroke Etiology (BASE) Study Methodology
Acute ischemic stroke affects over 800,000 US adults annually, with hundreds of thousands more experiencing a transient ischemic attack. Emergent evaluation, prompt acute treatment, and identification of strok...
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External validation of a claims-based and clinical approach for predicting post-pulmonary embolism outcomes among United States veterans
The In-hospital Mortality for PulmonAry embolism using Claims daTa (IMPACT) rule can accurately identify pulmonary embolism (PE) patients at low risk of early complications using claims data. We sought to exte...
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Open AccessEchocardiography and lung ultrasonography for the assessment and management of acute heart failure
Over-reliance of traditional clinical findings and symptoms can potentially delay diagnosis of acute heart failure (AHF), prolonging the time to appropriate th...
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Open AccessDischarge or admit? Emergency department management of incidental pulmonary embolism in patients with cancer: a retrospective study
Hospitalization and early anticoagulation therapy remain standard care for patients who present to the emergency department (ED) with pulmonary embolism (PE). For PEs discovered incidentally, however, optimal ...
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Hospital length-of-stay and costs among pulmonary embolism patients treated with rivaroxaban versus parenteral bridging to warfarin
We sought to compare length-of-stay (LOS), total hospital costs, and readmissions among pulmonary embolism (PE) patients treated with rivaroxaban versus parenterally bridged warfarin. We identified adult PE (p...
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Open AccessObservation management of pulmonary embolism and agreement with claims-based and clinical risk stratification criteria in United States patients: a retrospective analysis
Guidelines suggest observation stays are appropriate for pulmonary embolism (PE) patients at low-risk for early mortality. We sought to assess agreement between United States (US) observation management of PE ...
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Outcomes associated with observation stays versus inpatient admissions for pulmonary embolism
Changes in reimbursement policies have led to an increased use of observation stays in the United States (US). We sought to compare outcomes among pulmonary embolism (PE) patients managed through observation s...
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Open AccessExternal validation of a multivariable claims-based rule for predicting in-hospital mortality and 30-day post-pulmonary embolism complications
Low-risk pulmonary embolism (PE) patients may be candidates for outpatient treatment or abbreviated hospital stay. There is a need for a claims-based prediction rule that payers/hospitals can use to risk strat...
